Protein Domain : IPR028233

Type:  Family Name:  Cilia BBSome complex subunit 10
Description:  The BBSome (so-named after the association with Bardet-Biedl syndrome) is a complex of 8 subunits that lies at the base of the flagellar microtubule structure. The precise function of the all the individual components in cilia formation is unclear; however, they function to promote loading of cargo to the ciliary axoneme []. BBIP10 localises to the primary cilium, and is present exclusively in ciliated organisms. It is required for cytoplasmic microtubule polymerisation and acetylation, two functions not shared with any other BBSome subunits. BBIP10 physically interacts with HDAC6. BBSome-bound BBIP10 may therefore function to couple acetylation of axonemal microtubules and ciliary membrane growth []. Short Name:  BBIP10
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0 Child Features

0 Contains

1 Cross References

Identifier
PF14777

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0042384 IPR028233
GO:0034464 IPR028233

2 Ontology Annotations

GO Term Gene Name
GO:0042384 IPR028233
GO:0034464 IPR028233

0 Parent Features

3 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
60257 C1EB02 PAC:27404587 Micromonas sp RCC299 81  
Dusal.0305s00005.1.p PAC:33191332 Dunaliella salina 68  
Cz16g20050.t1 PAC:38239229 Chromochloris zofingiensis 74  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17574030
            19081074