Protein Domain : IPR028928

Type:  Domain Name:  CC2D2A, N-terminal, C2 domain
Description:  A C2 domain is usually involved in targeting proteins to cell membranes. Ciliary CC2D2A protein has two C2 domains and an inactive transglutaminase-like peptidase domain (CC2D2A-TGL) []. This entry represents the first C2 domain. CC2D2A (coiled-coil and C2 domain-containing protein 2A) is a component of the tectonic-like complex, a complex localised at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes []. It is required for ciliogenesis and sonic hedgehog/SHH signalling []. Short Name:  CC2D2AN-C2
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0 Child Features

0 Contains

1 Cross References

Identifier
PF15625

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

6 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
58671 C1MU53 PAC:27347965 Micromonas pusilla CCMP1545 1459  
56742 C1E146 PAC:27398395 Micromonas sp RCC299 1419  
Cre16.g660750.t1.1 A0A2K3CTH6 PAC:30777364 Chlamydomonas reinhardtii 2093  
Dusal.0179s00004.1.p PAC:33190117 Dunaliella salina 1728  
Cz03g25050.t1 PAC:38241448 Chromochloris zofingiensis 1815  
Vocar.0004s0137.1.p PAC:32889428 Volvox carteri 1960  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            22983010
            18513680
            22179047