Protein Domain : IPR000100

Type:  Family Name:  Ribonuclease P
Description:  Ribonuclease P () (RNase P) [, , ] is a site specific endonuclease that generates mature tRNAs by catalysing the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. In bacteria RNase P is known to be composed of two components: a large RNA (about 400 base pairs) encoded by rnpB, and a small protein (119 to 133 amino acids) encoded by rnpA. The RNA moiety of RNase P carries the catalytic activity; the protein component plays an auxiliary, but essential, role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.The sequence of rnpA is not highly conserved, however there is, in the central part of the protein, a conserved basic region. Short Name:  RNase_P
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0 Child Features

1 Contains

DB identifier Type Name
IPR020539 Conserved_site Ribonuclease P, conserved site

4 Cross Referencess

Identifier
PF00825
PD003629
TIGR00188
MF_00227

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0000049 IPR000100
GO:0004526 IPR000100
GO:0008033 IPR000100

3 Ontology Annotations

GO Term Gene Name
GO:0000049 IPR000100
GO:0004526 IPR000100
GO:0008033 IPR000100

0 Parent Features

8 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
56797 C1MN64 PAC:27347241 Micromonas pusilla CCMP1545 344  
58332 C1E5I9 PAC:27395276 Micromonas sp RCC299 393  
27050 A4S6A8 PAC:27418616 Ostreococcus lucimarinus 164  
Thecc1EG037322t5 A0A061GKK6 PAC:27429896 Theobroma cacao 474  
Caamp.0004s0310.2.p PAC:39104063 Caulanthus amplexicaulis 416  
Caamp.0004s0310.1.p PAC:39104062 Caulanthus amplexicaulis 540  
MD10G1336000 PAC:40091581 Malus domestica 209  
Gotom.D06G107800.1.p A0A5D2KHB6 PAC:42177792 Gossypium tomentosum 408  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            1700778
            1689306
            1374553