| Type: | Domain | Name: | Integrase, N-terminal zinc-binding domain-like |
| Description: | This entry represents a structural domain with an alpha-helical, orthogonal bundle fold. Domains with this structure are found at the N-terminal (zinc-binding domain) of HIV integrase, and in the following hypothetical proteins: YebC from Escherichia coli, HP0162 from Helicobacter pylori(Campylobacter pylori) and aq1575 from Aquifex aeolicus[].Retroviral integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains: an N-terminal zinc binding domain, a central catalytic core and a C-terminal DNA-binding domain [, ]. It is often found as part of the POL polyprotein. | Short Name: | Integrase_Zn-bd_dom-like_N |
