| Type: | Domain | Name: | Nitrophenylphosphatase-like domain |
| Description: | The haloacid dehydrogenase (HAD) superfamily includes phosphatases, phosphonatases, P-type ATPases, beta-phosphoglucomutases, phosphomannomutases, and dehalogenases, which are involved in a variety of cellular processes ranging from amino acid biosynthesis to detoxification [].Crystal structures of proteins from the HAD superfamily show that these proteins all share a conserved alpha/beta-domain classified as a hydrolase fold, which is similar to the Rossmann fold []. This conserved domain usually contains an insertion domain. The insertion domain shows structural variation among the different functional classes of the haloacid dehalogenase superfamily.This entry represents a Rossmann fold insertion domain found in some HAD members, including 4-nitrophenylphosphatase. | Short Name: | NPhePase-like_dom |
