3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0005524 | IPR004487 |
| GO:0051082 | IPR004487 |
| GO:0006457 | IPR004487 |
| Type: | Family | Name: | Clp protease, ATP-binding subunit ClpX |
| Description: | ClpX is a member of the HSP (heat-shock protein) 100 family. Gel filtration and electron microscopy showed that ClpX subunits associate to form a six-membered ring that is stabilised by binding of ATP or nonhydrolysable analogs of ATP []. It functions as an ATP-depedent [] molecular chaperone and is the regulatory subunit of the ClpXP protease [].ClpXP is involved in DNA damage repair, stationary-phase gene expression, and ssrA-mediated protein quality control. To date more than 50 proteins include transcription factors, metabolic enzymes, and proteins involved in the starvation and oxidative stress responses have been identified as substrates []. The N-terminal domain of ClpX is a C4-type zinc binding domain (ZBD) involved in substrate recognition. ZBD forms a very stable dimer that is essential for promoting the degradation of some typical ClpXP substrates such as lO and MuA []. | Short Name: | Clp_protease_ATP-bd_su_ClpX |
| GO Term | Gene Name |
|---|---|
| GO:0005524 | IPR004487 |
| GO:0051082 | IPR004487 |
| GO:0006457 | IPR004487 |
