| Type: | Domain | Name: | AhpD-like |
| Description: | This entry represents the alpha-helical domain found in alkyl-hydroperoxide reductase AhpD []. AhpD is a component of alkyl-hydroperoxide reductase participating in defense against ROS (reactive oxygen species) []. The C-terminal alpha-helical domain of the AhpD protein from Mycobacterium tuberculosis shares protein sequence and structural similarity with the N-terminal of Sesns from animals []. Sestrins (Sesns) are involved in ROS (reactive oxygen species) regulation []. A similar fold can also be found in other proteins such as 4-carboxymuconolactone decarboxylase (CMD) and some uncharacterised proteins []. | Short Name: | AhpD-like |
