Type: | Family | Name: | Caskin/Ankyrin repeat-containing protein |
Description: | This entry consists of Caskin 1 and 2 (containing six N-terminal ankyrin repeats) and ankyrin repeat containing proteins. The conserved fold of the ankyrin repeat unit is known from several crystal and solution structures [, , , ]. Each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90oangle. The repeats stack together to form an L-shaped structure [, ].Caskin 1 may link the scaffolding protein CASK to downstream intracellular effectors []. Ankyrin repeat-containing protein At3g12360 (also known as ITN1) from Arabidopsis is involved in salt tolerance and may promote ROS production []. | Short Name: | Caskin/Ankyrin_rpt_con_pro |