Protein Domain : IPR017151

Type:  Family Name:  5'-3' exoribonuclease 2/3
Description:  5'-3'-exoribonucleases are enzymes that degrade RNA by removing terminal nucleotides from the 5' end. Hydrolytic exoribonucleases, to which this entry belongs, produce nucleotide monosphosphates. An exosome and a 5'-3'-exoribonuclease are important in the degradation of very unstable transcripts [].5'-3' exoribonuclease 2 (Xrn2) and 5'-3' exoribonuclease 3 (Xrn3) act as post-transcriptional gene silencing (PTGS) suppressors []. Xrn2, also known as Rat1, occurs in animal, plant and fungal lineages. In Saccharomyces cerevisiae, Rat1 serves to terminate RNA polymerase II (RNAPII) molecules engaged in the production of uncapped RNA []. Short Name:  5_3_exoribonuclease_2/3
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0 Child Features

2 Contains

DB identifier Type Name
IPR001878 Domain Zinc finger, CCHC-type
IPR004859 Domain Putative 5-3 exonuclease

1 Cross References

Identifier
PIRSF037239

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004534 IPR017151
GO:0006139 IPR017151
GO:0005634 IPR017151

3 Ontology Annotations

GO Term Gene Name
GO:0004534 IPR017151
GO:0006139 IPR017151
GO:0005634 IPR017151

1 Parent Features

DB identifier Type Name
IPR027073 Family 5'-3' exoribonuclease

513 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Lus10024327 PAC:23175012 Linum usitatissimum 993  
Araha.10772s0004.2.p PAC:28860053 Arabidopsis halleri 1054  
Araha.10772s0004.1.p PAC:28860052 Arabidopsis halleri 1054  
Traes_3B_1A1DD4EBC.4 PAC:31821763 Triticum aestivum 838  
GSMUA_Achr8P07320_001 PAC:32312096 Musa acuminata 972  
Brdisv1Gaz-81024772m.p PAC:33816147 Brachypodium distachyon Gaz-8 737  
Brdisv1Gaz-81024771m.p PAC:33816146 Brachypodium distachyon Gaz-8 974  
Brdisv1BdTR2G1019936m.p PAC:35067991 Brachypodium distachyon BdTR2g 745  
Brdisv1BdTR2G1019935m.p PAC:35067990 Brachypodium distachyon BdTR2g 1046  
Brdisv1Adi-101015304m.p PAC:35706725 Brachypodium distachyon Adi-10 745  
Brdisv1Adi-101015303m.p PAC:35706724 Brachypodium distachyon Adi-10 1046  
AUR62040580-RA PAC:36297381 Chenopodium quinoa 1065  
Phvul.001G007900.1.p V7CRE4 PAC:37170792 Phaseolus vulgaris 1067  
Phvul.003G280400.1.p V7CG77 PAC:37144836 Phaseolus vulgaris 1057  
Zm00008a015484_P01 K7UB09 PAC:37194672 Zea mays PH207 1058  
Potri.002G024100.2.p A0A3N7EL97 PAC:37258698 Populus trichocarpa 632  
Potri.005G237500.3.p A0A2K2ALL7 PAC:37265619 Populus trichocarpa 1096  
Potri.005G237500.1.p A0A2K2ALK5 PAC:37265618 Populus trichocarpa 1098  
Potri.005G237500.2.p B9H4V3 PAC:37265617 Populus trichocarpa 1102  
Podel.05G253300.1.p PAC:37318370 Populus deltoides WV94 1106  
Podel.02G024200.1.p PAC:37296534 Populus deltoides WV94 1041  
Bol039293 PAC:37357843 Brassica oleracea capitata 1031  
Bol027710 PAC:37365709 Brassica oleracea capitata 1017  
AT5G42540.2 F4K1L3 PAC:37417363 Arabidopsis thaliana 1023  
AT5G42540.1 Q9FQ02 PAC:37417364 Arabidopsis thaliana 1012  
AT1G75660.1 Q9FQ03 PAC:37397129 Arabidopsis thaliana 1020  
PGSC0003DMP400006645 PAC:37473425 Solanum tuberosum 1099  
Anaoc.0009s0248.1.p PAC:37499200 Anacardium occidentale 1042  
Pavir.5NG173600.1.p PAC:37572490 Panicum virgatum 1068  
Pavir.6NG083000.1.p PAC:37648398 Panicum virgatum 1061  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            18481995
            20188675
            17993620