Protein Domain : IPR010060

Type:  Domain Name:  Non-ribosomal peptide synthase
Description:  This entry represents a region of 171 amino acids long and contains three very highly conserved regions. At the N terminus is a nearly invariant lysine (position 11) followed by xxxRxxPxxGxGYG in which the proline and the first glycine are invariant. This is followed approximately 22 residues later by the motif FNYLG. Near the C terminus of the domain is the sequence TxSD where the serine and aspartate are nearly invariant. This domain appears to be located immediately downstream from a condensation domain (), and is followed primarily by the end of the molecule or another condensation domain (or, in a few cases, it is followed by , an AMP-binding module). The converse is not true, domains are not always followed by this domain, which implicates this domain in possible post-condensation modification events.This region has so far been found in a variety of peptide synthases including Bacitracin synthetase 1 []Gramicidin S synthetase 1 []Linear gramicidin synthetase subunit A []Surfactin synthetase subunit 1 []Tyrocidine synthetase 1 [] Short Name:  NRPS_synth
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0 Child Features

0 Contains

1 Cross References

Identifier
TIGR01720

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

6 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1008817m.p PAC:33619101 Brachypodium distachyon Pangenome 2608  
Brdisv1pangenome1009708m.p PAC:33657087 Brachypodium distachyon Pangenome 2694  
Brdisv1BdTR11A1040687m.p PAC:35690640 Brachypodium distachyon BdTR11a 3380  
Brdisv1BdTR11A1040342m.p PAC:35688846 Brachypodium distachyon BdTR11a 4923  
Brdisv1BdTR11A1040435m.p PAC:35692712 Brachypodium distachyon BdTR11a 4330  
Brdisv1BdTR11A1041037m.p PAC:35687897 Brachypodium distachyon BdTR11a 2417  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9427658
            7718566
            14670971
            1847909
            2768192