Protein Domain : IPR003710

Type:  Family Name:  Ketopantoate reductase ApbA/PanE
Description:  ApbA, the ketopantoate reductase enzyme of Salmonella typhimuriumis required for the synthesis of thiamine via the alternative pyrimidine biosynthetic pathway []. Precursors to the pyrimidine moiety of thiamine are synthesized de novo by the purine biosynthetic pathway or the alternative pyrimidine biosynthetic (APB) pathway. The ApbA protein catalyzes the NADPH-specific reduction of ketopantoic acid to pantoic acid. This activity had previously been associated with the pantothenate biosynthetic gene panE []. ApbA and PanE are allelic []. Short Name:  ApbA
Paste the following link

0 Child Features

2 Contains

DB identifier Type Name
IPR013332 Domain Ketopantoate reductase, N-terminal domain
IPR013752 Domain Ketopantoate reductase, C-terminal domain

1 Cross References

Identifier
TIGR00745

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0016491 IPR003710
GO:0015940 IPR003710
GO:0055114 IPR003710
GO:0005737 IPR003710

4 Ontology Annotations

GO Term Gene Name
GO:0016491 IPR003710
GO:0015940 IPR003710
GO:0055114 IPR003710
GO:0005737 IPR003710

0 Parent Features

3 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1008681m.p PAC:33657092 Brachypodium distachyon Pangenome 585  
Brdisv1BdTR11A1044715m.p PAC:35690919 Brachypodium distachyon BdTR11a 585  
Cocit.L4763.1.p PAC:41063287 Corymbia citriodora 354  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9488683
            9721324