Protein Domain : IPR005753

Type:  Family Name:  DNA helicase, ATP-dependent, UvrD type
Description:  The SOS response is required for efficient nucleotide excision repair (NER) of the major ultraviolet light (UV) induced DNA lesions. The expression of three NER genes, uvrA, uvrB, and uvrD, is upregulated as part of the SOS response. UvrD differs from the others in that it is not involved in lesion recognition but rather in promoting the post-incision steps of NER, including turnover of the UvrBC incision complex []. The form of the UvrD helicase with optimal helicase activity is oligomeric with at least two sites for binding the DNA substrate, where one site contacts regions of the 3'-ssDNA tail that are distal from the single-stranded/double-stranded DNA junction. Short Name:  DNA_helicase_ATP-dep_UvrD
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0 Child Features

2 Contains

DB identifier Type Name
IPR014017 Domain UvrD-like DNA helicase, C-terminal
IPR014016 Domain UvrD-like Helicase, ATP-binding domain

1 Cross References

Identifier
TIGR01075

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004003 IPR005753
GO:0006268 IPR005753
GO:0005737 IPR005753

3 Ontology Annotations

GO Term Gene Name
GO:0004003 IPR005753
GO:0006268 IPR005753
GO:0005737 IPR005753

1 Parent Features

DB identifier Type Name
IPR000212 Family DNA helicase, UvrD/REP type

4 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1008147m.p PAC:33640683 Brachypodium distachyon Pangenome 643  
Brdisv1pangenome1010088m.p PAC:33607426 Brachypodium distachyon Pangenome 774  
Brdisv1BdTR11A1043470m.p PAC:35692776 Brachypodium distachyon BdTR11a 632  
Brdisv1BdTR11A1040781m.p PAC:35689338 Brachypodium distachyon BdTR11a 1048  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11585364