Protein Domain : IPR006417

Type:  Domain Name:  Nicotinamide-nucleotide adenylyltransferase
Description:  The NadR protein of Escherichia coliand closely related bacteria is both enzyme and regulatory protein. The first 60 or so amino acids, N-terminal region is a DNA-binding helix-turn-helix domain () responsible for repressing the nadAB genes of NAD de novo biosynthesis. The NadR homologues in Mycobacterium tuberculosis, Haemophilus influenzae, amongst others, appear to lack the repressor domain. NadR has recently been shown to act as an enzyme of the salvage pathway of NAD biosynthesis, nicotinamide-nucleotide adenylyltransferase; members of this family are presumed to share this activity. E. coli NadR has also been found to regulate the import of its substrate, nicotinamide ribonucleotide, but it is not known if the other members of this family share that activity. Short Name:  NadR_NMN_Atrans
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0 Child Features

1 Contains

DB identifier Type Name
IPR004821 Domain Cytidyltransferase-like domain

1 Cross References

Identifier
TIGR01526

1 Found In

DB identifier Type Name
IPR016429 Family Bifunctional transcriptional regulator NadR

4 GO Annotations

GO Term Gene Name
GO:0003677 IPR006417
GO:0006355 IPR006417
GO:0006810 IPR006417
GO:0019363 IPR006417

4 Ontology Annotations

GO Term Gene Name
GO:0003677 IPR006417
GO:0006355 IPR006417
GO:0006810 IPR006417
GO:0019363 IPR006417

0 Parent Features

2 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1007307m.p PAC:33640678 Brachypodium distachyon Pangenome 806  
Brdisv1BdTR11A1042166m.p PAC:35697261 Brachypodium distachyon BdTR11a 806  

0 Publications