Protein Domain : IPR005921

Type:  Family Name:  Histidine ammonia-lyase
Description:  Histidine ammonia-lyase deaminates histidine to urocanic acid, the first step in histidine degradation. It is closely related to the plant enzyme phenylalanine ammonia-lyase [] but is absent in plants and viruses. This enzyme contains a unique cofactor called 4-methylidene-imidazole-5-one group (MIO), which is produced autocatalytically by a cyclization and dehydration of the three amino-acid residues alanine, serine and glycine, for its chain folding []. Short Name:  HutH
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0 Child Features

2 Contains

DB identifier Type Name
IPR008948 Domain L-Aspartase-like
IPR022313 Active_site Phenylalanine/histidine ammonia-lyases, active site

2 Cross Referencess

Identifier
TIGR01225
MF_00229

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0004397 IPR005921
GO:0006548 IPR005921
GO:0005737 IPR005921

3 Ontology Annotations

GO Term Gene Name
GO:0004397 IPR005921
GO:0006548 IPR005921
GO:0005737 IPR005921

1 Parent Features

DB identifier Type Name
IPR001106 Family Aromatic amino acid lyase

14 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Brdisv1pangenome1005589m.p PAC:33658873 Brachypodium distachyon Pangenome 491  
Brdisv1pangenome1007388m.p PAC:33607789 Brachypodium distachyon Pangenome 498  
Brdisv1pangenome1007389m.p PAC:33607788 Brachypodium distachyon Pangenome 490  
Brdisv1pangenome1009344m.p PAC:33607423 Brachypodium distachyon Pangenome 509  
Brdisv1pangenome1008887m.p PAC:33655860 Brachypodium distachyon Pangenome 544  
Brdisv1pangenome1009470m.p PAC:33641272 Brachypodium distachyon Pangenome 549  
Brdisv1pangenome1009640m.p PAC:33624081 Brachypodium distachyon Pangenome 442  
Brdisv1BdTR11A1046167m.p PAC:35690518 Brachypodium distachyon BdTR11a 529  
Brdisv1BdTR11A1046527m.p PAC:35691208 Brachypodium distachyon BdTR11a 501  
Brdisv1BdTR11A1029432m.p PAC:35683097 Brachypodium distachyon BdTR11a 491  
Brdisv1BdTR11A1045159m.p PAC:35695684 Brachypodium distachyon BdTR11a 544  
Brdisv1BdTR11A1042272m.p PAC:35689151 Brachypodium distachyon BdTR11a 490  
Brdisv1BdTR11A1042271m.p PAC:35696486 Brachypodium distachyon BdTR11a 498  
Brdisv1BdTR11A1040662m.p PAC:35688315 Brachypodium distachyon BdTR11a 1022  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10220322
            11796111