Protein Domain : IPR016105

Type:  Domain Name:  Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain
Description:  This entry represents a structural subdomain found in pyruvoyl-dependent histidine decarboxylase () and arginine decarboxylase (). This subdomain consists of a 3-layer beta-beta-alpha sandwich. These proteins form heterohexamers [, ].Histidine decarboxylase catalyses the formation of histamine from histidine. It requires a pyruvoyl group for its activity. Cleavage of the proenzyme PI chain yields two subunits, alpha and beta, which arrange as a hexamer (alpha beta) 6 by nonhydrolytic self-catalysis.Arginine decarboxylase catalyses the interconversion of arginine and agmatine plus carbon dioxide. It requires a pyruvoyl group for its activity. Short Name:  Pyr-dep_his/arg-deCO2ase_sand
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0 Child Features

0 Contains

1 Cross References

Identifier
G3DSA:3.50.20.10

3 Found Ins

DB identifier Type Name
IPR016104 Domain Pyruvoyl-dependent histidine/arginine decarboxylase
IPR002724 Family Pyruvoyl-dependent arginine decarboxylase
IPR003427 Family Histidine decarboxylase proenzyme

2 GO Annotations

GO Term Gene Name
GO:0016831 IPR016105
GO:0006520 IPR016105

2 Ontology Annotations

GO Term Gene Name
GO:0016831 IPR016105
GO:0006520 IPR016105

0 Parent Features

221 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
Thhalv10016231m V4M956 PAC:20180077 Eutrema salsugineum 861  
Lus10029202 PAC:23151695 Linum usitatissimum 413  
Gorai.012G123200.1 A0A0D2VYL5 PAC:26827982 Gossypium raimondii 410  
Gorai.012G123200.2 A0A0D2VYL5 PAC:26827981 Gossypium raimondii 410  
Gorai.012G123200.3 A0A0D2S1Y0 PAC:26827983 Gossypium raimondii 354  
Gorai.012G123200.6 A0A0D2V4L1 PAC:26827985 Gossypium raimondii 301  
59611 PAC:27402451 Micromonas sp RCC299 274  
Thecc1EG011895t1 A0A061ECT0 PAC:27460150 Theobroma cacao 60  
Glyma.02G029600.2.p I1JBX9 PAC:30509350 Glycine max 413  
Glyma.02G029600.1.p I1JBX9 PAC:30509349 Glycine max 413  
Brara.G02516.1.p A0A397YPN4 PAC:30634851 Brassica rapa FPsc 126  
Cre14.g610700.t1.1 A0A2K3CX81 PAC:30776111 Chlamydomonas reinhardtii 758  
Medtr3g103990.1 G7J717 PAC:31057526 Medicago truncatula 117  
Spipo0G0163000 PAC:31507717 Spirodela polyrhiza 526  
Traes_1DL_43162594B.1 PAC:31922465 Triticum aestivum 170  
Traes_4AL_CB8D23679.1 PAC:31984263 Triticum aestivum 253  
Traes_5AL_FF3020C47.1 PAC:31797384 Triticum aestivum 70  
Traes_5AL_FF3020C47.2 PAC:31797382 Triticum aestivum 80  
Traes_5BL_E17023FD1.5 PAC:31749982 Triticum aestivum 540  
Traes_5BL_E17023FD1.3 PAC:31749981 Triticum aestivum 540  
Traes_5BL_E17023FD1.10 PAC:31749985 Triticum aestivum 537  
Traes_5BL_E17023FD1.8 PAC:31749984 Triticum aestivum 540  
Traes_5BL_E17023FD1.4 PAC:31749983 Triticum aestivum 540  
Traes_5BL_E17023FD1.11 PAC:31749987 Triticum aestivum 537  
Traes_5BL_E17023FD1.9 PAC:31749986 Triticum aestivum 537  
Traes_5BL_E17023FD1.6 PAC:31749980 Triticum aestivum 540  
Traes_5BL_E17023FD1.7 PAC:31749979 Triticum aestivum 540  
Traes_5BL_E17023FD1.2 PAC:31749978 Triticum aestivum 547  
Traes_5BL_D1DC469A1.2 PAC:31983006 Triticum aestivum 116  
Traes_5DL_02D649D6E.1 PAC:31981673 Triticum aestivum 190  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12623016
            11243783