Protein Domain : IPR020189

Type:  Domain Name:  Translation elongation factor, IF5A C-terminal
Description:  A five-stranded beta-barrel was first noted as a common structure among four proteins binding single-stranded nucleic acids (staphylococcal nuclease and aspartyl-tRNA synthetase) or oligosaccharides (B subunits of enterotoxin and verotoxin-1), and has been termed the oligonucleotide/oligosaccharide binding motif, or OB fold, a five-stranded beta-sheet coiled to form a closed beta-barrel capped by an alpha helix located between the third and fourth strands []. Two ribosomal proteins, S17 and S1, are members of this class, and have different variations of the OB fold theme. Comparisons with other OB fold nucleic acid binding proteins suggest somewhat different mechanisms of nucleic acid recognition in each case [].There are many nucleic acid-binding proteins that contain domains with this OB-fold structure, including anticodon-binding tRNA synthetases, ssDNA-binding proteins (CDC13, telomere-end binding proteins), phage ssDNA-binding proteins (gp32, gp2.5, gpV), cold shock proteins, DNA ligases, RNA-capping enzymes, DNA replication initiators and RNA polymerase subunit RBP8 [].This entry represents the RNA-binding domain of translation elongation factor IF5A []. Short Name:  Transl_elong_IF5A_C
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0 Child Features

0 Contains

1 Cross References

Identifier
PF01287

1 Found In

DB identifier Type Name
IPR001884 Family Translation elongation factor IF5A

6 GO Annotations

GO Term Gene Name
GO:0003723 IPR020189
GO:0003746 IPR020189
GO:0043022 IPR020189
GO:0006452 IPR020189
GO:0045901 IPR020189
GO:0045905 IPR020189

6 Ontology Annotations

GO Term Gene Name
GO:0003723 IPR020189
GO:0003746 IPR020189
GO:0043022 IPR020189
GO:0006452 IPR020189
GO:0045901 IPR020189
GO:0045905 IPR020189

1 Parent Features

DB identifier Type Name
IPR012340 Domain Nucleic acid-binding, OB-fold

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
142541 D8R032 PAC:15413434 Selaginella moellendorffii 159  
evm.model.supercontig_1.78 PAC:16404424 Carica papaya 159  
evm.model.supercontig_1348.1 PAC:16408244 Carica papaya 160  
evm.model.supercontig_1469.1 PAC:16409181 Carica papaya 159  
30138.m004031 B9RLU3 PAC:16819396 Ricinus communis 160  
30174.m009164 B9RCY4 PAC:16822804 Ricinus communis 509  
29687.m000560 B9STQ5 PAC:16805814 Ricinus communis 160  
Cucsa.093380.1 A0A0A0LTB3 PAC:16957611 Cucumis sativus 160  
Cucsa.271540.1 A0A0A0L5K9 PAC:16973544 Cucumis sativus 159  
Cucsa.271540.2 PAC:16973545 Cucumis sativus 133  
Cucsa.271540.3 PAC:16973546 Cucumis sativus 122  
Cucsa.162830.1 A0A0A0LPT1 PAC:16965743 Cucumis sativus 160  
Cucsa.284720.1 A0A0A0KU59 PAC:16974736 Cucumis sativus 159  
orange1.1g031387m A0A067EWH2 PAC:18122075 Citrus sinensis 160  
orange1.1g030552m A0A067F7H8 PAC:18122074 Citrus sinensis 175  
orange1.1g031432m A0A067GTT5 PAC:18102835 Citrus sinensis 159  
orange1.1g033076m A0A067H670 PAC:18102837 Citrus sinensis 128  
orange1.1g031466m A0A067GTT5 PAC:18102836 Citrus sinensis 159  
AT1G13950.1 Q9XI91 PAC:19651718 Arabidopsis thaliana 158  
AT1G69410.1 Q9C505 PAC:19651246 Arabidopsis thaliana 158  
AT1G26630.1 Q93VP3 PAC:19651381 Arabidopsis thaliana 159  
AT1G26630.2 Q93VP3 PAC:19651382 Arabidopsis thaliana 138  
Thhalv10008978m V4KZF6 PAC:20188522 Eutrema salsugineum 158  
Thhalv10008974m V4KSK5 PAC:20186107 Eutrema salsugineum 159  
Thhalv10019263m V4KEQ8 PAC:20191454 Eutrema salsugineum 158  
Ciclev10022624m V4TVG1 PAC:20808499 Citrus clementina 160  
Ciclev10022848m V4TKH8 PAC:20808500 Citrus clementina 129  
Ciclev10009759m V4UVY7 PAC:20795766 Citrus clementina 160  
Ciclev10032954m V4TK45 PAC:20804681 Citrus clementina 159  
Ciclev10032956m V4TK45 PAC:20804680 Citrus clementina 159  

4 Publications

First Author Title Year Journal Volume Pages PubMed ID
            19424157
            15178340
            9862955
            12769718