Protein Domain : IPR019495

Type:  Family Name:  Exosome complex component CSL4
Description:  Exosome is a complex of 3' -->5' exoribonucleases that play a major role in diverse RNA processing and degradation pathways. The eukaryotic exosome complex contains 9 proteins. Six RNase PH domain containing proteins (Rrp41, Rrp42, Rrp43, Rrp45, Rrp46, and Mtr3) form a catalytic ring, three RNA binding domain containing proteins (Rrp4,Rrp40, and Csl4) bind on top of the ring [].This entry includes the exosome complex component CSL4 (also known as EXOSC1). It does not have exonuclease activity, but are required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA and for mRNA decay [, ]. Short Name:  EXOSC1
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0 Child Features

0 Contains

1 Cross References

Identifier
PF10447

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0003723 IPR019495
GO:0000178 IPR019495

2 Ontology Annotations

GO Term Gene Name
GO:0003723 IPR019495
GO:0000178 IPR019495

0 Parent Features

384 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
175887 D8S0J7 PAC:15401443 Selaginella moellendorffii 197  
29680.m001733 B9S7P6 PAC:16805563 Ricinus communis 593  
Cucsa.150320.1 A0A0A0L935 PAC:16964412 Cucumis sativus 196  
orange1.1g029155m A0A067EBM7 PAC:18093715 Citrus sinensis 198  
orange1.1g032149m A0A067EEZ8 PAC:18093716 Citrus sinensis 146  
orange1.1g028346m A0A067EBA0 PAC:18093714 Citrus sinensis 210  
AT5G38890.1 A2RVT9 PAC:19668596 Arabidopsis thaliana 191  
Thhalv10019185m V4KMU5 PAC:20191786 Eutrema salsugineum 189  
Ciclev10022721m V4TSU2 PAC:20809073 Citrus clementina 146  
Ciclev10022342m V4U2X3 PAC:20809072 Citrus clementina 198  
Lus10004763 PAC:23140482 Linum usitatissimum 163  
Lus10003098 PAC:23165940 Linum usitatissimum 171  
Potri.013G049800.1 A0A2K1Y164 PAC:26995914 Populus trichocarpa 199  
Potri.013G050400.1 A9PBL9 PAC:26995454 Populus trichocarpa 199  
Gorai.013G188600.1 A0A0D2VGS7 PAC:26789768 Gossypium raimondii 222  
Gorai.013G188600.2 A0A0D2U312 PAC:26789769 Gossypium raimondii 195  
52805 I0Z3L8 PAC:27389842 Coccomyxa subellipsoidea C-169 190  
154658 C1MR50 PAC:27346059 Micromonas pusilla CCMP1545 196  
98947 C1E0K6 PAC:27396450 Micromonas sp RCC299 202  
8172 A4S034 PAC:27414165 Ostreococcus lucimarinus 127  
Thecc1EG026126t2 A0A061F8I4 PAC:27425351 Theobroma cacao 192  
Thecc1EG026126t3 A0A061F0F8 PAC:27425349 Theobroma cacao 221  
Thecc1EG026126t1 A0A061F1N6 PAC:27425350 Theobroma cacao 194  
Thecc1EG026126t4 A0A061F195 PAC:27425352 Theobroma cacao 169  
Thecc1EG032443t1 A0A061FAR4 PAC:27444323 Theobroma cacao 104  
Migut.F02051.1.p A0A022RHS0 PAC:28932755 Mimulus guttatus 198  
Araha.2301s0005.1.p PAC:28847590 Arabidopsis halleri 191  
Cagra.15542s0001.1.p PAC:28903220 Capsella grandiflora 175  
Glyma.10G167500.1.p K7LJV1 PAC:30473952 Glycine max 197  
Glyma.20G221600.1.p A0A0R0ENA0 PAC:30519894 Glycine max 175  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17174896
            10465791
            17173052