Type: | Family | Name: | Rcd1/Caf40 |
Description: | This entry includes Rcd1 and its homologue in budding yeast, Caf40. Mammalian Rcd1 is a component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation [].Caf40 is a component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover []. | Short Name: | Rcd1/Caf40 |