Protein Domain : IPR018491

Type:  Domain Name:  SLC12A transporter, C-terminal
Description:  This entry represents a domain found in the C-terminal of the solute carrier family 12 (SLC12) members, which are K-Cl cotransporters. The SLC12 family members are predicted to have 12 transmembrane (TM) regions in a central hydrophobic domain, together with hydrophilic N- and C-termini that are likely cytoplasmic. Comparison of their sequences with those of other ion-tranporting membrane proteins reveals that they are part of a new superfamily of cation-chloride co-transporters, which includes the Na-Cl and Na-K-2Cl co-transporters [, , ]. Short Name:  SLC12_C
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0 Child Features

0 Contains

1 Cross References

Identifier
PF03522

3 Found Ins

DB identifier Type Name
IPR004842 Family SLC12A transporter family
IPR000076 Family K/Cl co-transporter
IPR000622 Family K/Cl co-transporter 1

3 GO Annotations

GO Term Gene Name
GO:0005215 IPR018491
GO:0006811 IPR018491
GO:0016020 IPR018491

3 Ontology Annotations

GO Term Gene Name
GO:0005215 IPR018491
GO:0006811 IPR018491
GO:0016020 IPR018491

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
150343 D8RVK6 PAC:15413249 Selaginella moellendorffii 880  
425250 D8SSH6 PAC:15403562 Selaginella moellendorffii 1053  
evm.model.supercontig_17.78 PAC:16410803 Carica papaya 984  
29932.m000607 B9SKU4 PAC:16814092 Ricinus communis 976  
Cucsa.167150.1 PAC:16966244 Cucumis sativus 686  
orange1.1g002413m A0A067G6V3 PAC:18114610 Citrus sinensis 926  
orange1.1g002018m A0A067G9M5 PAC:18114609 Citrus sinensis 980  
orange1.1g005728m A0A067GJ14 PAC:18114611 Citrus sinensis 680  
AT1G30450.1 Q2UVJ5 PAC:19657376 Arabidopsis thaliana 975  
AT1G30450.2 Q2UVJ5 PAC:19657377 Arabidopsis thaliana 975  
AT1G30450.3 Q2UVJ5 PAC:19657378 Arabidopsis thaliana 975  
Thhalv10006695m V4K866 PAC:20186621 Eutrema salsugineum 976  
Ciclev10014154m V4W7M8 PAC:20815227 Citrus clementina 980  
Lus10003407 PAC:23169616 Linum usitatissimum 1117  
Lus10036156 PAC:23140990 Linum usitatissimum 963  
Lus10000067 PAC:23156268 Linum usitatissimum 245  
Potri.001G357600.1 PAC:27043737 Populus trichocarpa 783  
Potri.011G090900.1 A0A2K1YHM6 PAC:27000869 Populus trichocarpa 968  
Gorai.008G047100.2 A0A0D2PNU1 PAC:26813667 Gossypium raimondii 922  
Gorai.008G047100.1 A0A0D2R9G2 PAC:26813666 Gossypium raimondii 980  
Gorai.005G266600.3 A0A0D2SNX9 PAC:26802014 Gossypium raimondii 584  
Gorai.005G266600.4 A0A0D2NIQ9 PAC:26802015 Gossypium raimondii 477  
Gorai.005G266600.1 A0A0D2Q052 PAC:26802012 Gossypium raimondii 976  
Gorai.005G266600.2 A0A0D2RTU8 PAC:26802013 Gossypium raimondii 925  
60430 C1EBH3 PAC:27404675 Micromonas sp RCC299 1105  
Thecc1EG006088t1 A0A061DVX5 PAC:27460697 Theobroma cacao 979  
Migut.H01338.1.p PAC:28951813 Mimulus guttatus 992  
Araha.2050s0012.1.p PAC:28844135 Arabidopsis halleri 935  
Cagra.1508s0164.1.p PAC:28905721 Capsella grandiflora 969  
Glyma.09G085300.1.p K7LCK9 PAC:30486026 Glycine max 994  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            8663311
            9930699
            10600773