| Type: | Domain | Name: | Knottin, scorpion toxin-like |
| Description: | Proteins containing the knottin domain are restricted to the eukaryota. They are known as knottins or cystine-knot peptides and consists of small inhibitors, toxins and lectins . The scorpion toxin-like domain constitutes a subgroup, found in metazoan sequences mainly from the arthropoda, which include the antibacterial defensins and the scorpion alpha-neurotoxins. The plant sequences include members of the gamma-thionin family, which are plant defensins that have no antifungal activity. Other members are insect alpha -amylase inhibitors, cysteine-rich antifungal proteins and proteins annotated as proteinase inhibitors; those that are characterised belong to MEROPS inhibitor family I18, clan I. | Short Name: | Scorpion_toxin-like |
