Type: | Family | Name: | Piezo family |
Description: | Piezo ('piesi' meaning pressure in Greek) proteins are pore-forming subunits of mechanically-activated channels []. Expressing the proteins in mammalian cell lines has been shown to induce large mechanically-activated cationic currents []. In Drosophila, they have been shown to be involved in sensing noxious mechanical stimuli, but not gentle touch []. Piezo has been linked to Alzheimer disease in humans []. | Short Name: | Piezo |