Protein Domain : IPR026846

Type:  Family Name:  E3 SUMO-protein ligase Nse2 (Mms21)
Description:  This entry consists of the E3 SUMO-protein ligase Nse2 (also known as Mms21). Nse2 is an E3 SUMO-protein ligase component of the SMC5-SMC6 complex [, ]. Nse2 acts as an E3 ligase targeting several proteins for sumoylation and is required for efficient DNA repair and maintenance of genome stability [, , , ]. Nse2 and SMC5 may also be required for sister chromatid cohesion during prometaphase and mitotic progression; this role is apparently independent of SMC6 []. Nse2 is necessary for normal cell cycle progression in Arabidopsis, where Nse2 mutation results in abnormal root development []. Short Name:  Nse2(Mms21)
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR21330

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0019789 IPR026846
GO:0000724 IPR026846
GO:0030915 IPR026846

3 Ontology Annotations

GO Term Gene Name
GO:0019789 IPR026846
GO:0000724 IPR026846
GO:0030915 IPR026846

0 Parent Features

490 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
414614 D8RTD0 PAC:15418866 Selaginella moellendorffii 239  
424698 D8SQS3 PAC:15403774 Selaginella moellendorffii 214  
evm.model.supercontig_80.2 PAC:16426741 Carica papaya 246  
29705.m000587 B9SBA4 PAC:16806268 Ricinus communis 253  
Cucsa.122840.1 A0A0A0L3C3 PAC:16961511 Cucumis sativus 248  
orange1.1g025405m A0A067E5X5 PAC:18100954 Citrus sinensis 253  
orange1.1g025425m A0A067E225 PAC:18100955 Citrus sinensis 253  
orange1.1g029888m A0A067EED4 PAC:18100956 Citrus sinensis 186  
AT3G15150.1 Q8GYH7 PAC:19661710 Arabidopsis thaliana 249  
Thhalv10021394m V4LDC9 PAC:20182124 Eutrema salsugineum 249  
Ciclev10009269m V4UFX6 PAC:20792801 Citrus clementina 253  
Lus10015968 PAC:23169796 Linum usitatissimum 249  
Potri.011G141200.1 PAC:27002382 Populus trichocarpa 257  
Potri.011G141200.3 PAC:27002384 Populus trichocarpa 197  
Potri.011G141200.2 PAC:27002383 Populus trichocarpa 197  
Gorai.002G067000.1 A0A0D2NJ28 PAC:26796654 Gossypium raimondii 256  
41448 I0Z0J0 PAC:27390916 Coccomyxa subellipsoidea C-169 221  
Thecc1EG031645t1 A0A061F8U4 PAC:27445452 Theobroma cacao 275  
Thecc1EG031645t2 A0A061F8B6 PAC:27445453 Theobroma cacao 239  
Migut.M00775.1.p PAC:28950518 Mimulus guttatus 249  
Araha.43003s0008.1.p PAC:28856201 Arabidopsis halleri 249  
Cagra.0007s0058.1.p PAC:28903168 Capsella grandiflora 249  
Glyma.13G273500.1.p A0A0R0GUT5 PAC:30503952 Glycine max 247  
Glyma.13G273500.2.p A0A0R0H6U3 PAC:30503953 Glycine max 204  
Brara.E02627.1.p A0A397ZDE7 PAC:30626325 Brassica rapa FPsc 249  
Bostr.28625s0178.1.p PAC:30679461 Boechera stricta 249  
Bradi2g16585.1.p PAC:31116204 Brachypodium distachyon 496  
Medtr2g078640.1 A0A072VA32 PAC:31066547 Medicago truncatula 244  
SapurV1A.0047s0160.1.p PAC:31396451 Salix purpurea 258  
Spipo18G0014700 PAC:31518529 Spirodela polyrhiza 318  

8 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12966087
            15738391
            15601841
            16055714
            19502785
            19682286
            22921571
            21550342