Type: | Family | Name: | DAHP synthetase, class II |
Description: | Members of the 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthetase family () catalyse the first step in aromatic amino acid biosynthesis from chorismate. Class I (see ) includes bacterial and yeast enzymes; class II includes higher plants and various microorganisms [].The first step in the common pathway leading to the biosynthesis of aromatic compounds is the stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). This reaction is catalyzed by DAHP synthase, a metal-activated enzyme, which in microorganisms is the target for negative-feedback regulation by pathway intermediates or by end products. | Short Name: | DAHP_synth_2 |