Protein Domain : IPR025774

Type:  Family Name:  SAM-dependent methyltransferase gamma-tocopherol (gTMT)-type
Description:  This entry represents a subgroup of the class I SAM-dependent methyltransferases, including bacterial 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase [] and plant plastid tocopherol O-methyltransferase (also known as g-TMT (gamma-tocopherol methyltransferase)). Tocopherol O-methyltransferase is involved in the synthesis of tocopherol (vitamin E). It methylates gamma- and delta-tocopherol to form beta- and alpha-tocopherol, respectively [, , ].Methyltransferases (EC 2.1.1.-) constitute an important class of enzymes present in every life form. They transfer a methyl group most frequently from S-adenosyl L-methionine (SAM or AdoMet) to a nucleophilic acceptor such as oxygen leading to S-adenosyl-L-homocysteine (AdoHcy) and a methylated molecule [, , ]. All these enzymes have in common a conserved region of about 130 amino acid residues that allow them to bind SAM []. The substrates that are methylated by these enzymes cover virtually every kind of biomolecules ranging from small molecules, to lipids, proteins and nucleic acids [, , ]. Methyltransferase are therefore involved in many essential cellular processes including biosynthesis, signal transduction, protein repair, chromatin regulation and gene silencing [, , ]. More than 230 families of methyltransferases have been described so far, of which more than 220 use SAM as the methyl donor. Short Name:  MTs_g-TMT

0 Child Features

0 Contains

1 Cross References

Identifier
PS51581

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0051741 IPR025774
GO:0010189 IPR025774
GO:0032259 IPR025774

3 Ontology Annotations

GO Term Gene Name
GO:0051741 IPR025774
GO:0010189 IPR025774
GO:0032259 IPR025774

0 Parent Features

364 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
99567 PAC:15417382 Selaginella moellendorffii 320  
Cucsa.017420.1 A0A0A0LTM1 PAC:16951721 Cucumis sativus 344  
orange1.1g016942m A0A067EAQ8 PAC:18139614 Citrus sinensis 380  
orange1.1g016921m A0A067EAQ8 PAC:18139613 Citrus sinensis 380  
AT1G64970.1 Q9ZSK1 PAC:19656070 Arabidopsis thaliana 348  
Thhalv10018811m V4JU33 PAC:20191069 Eutrema salsugineum 346  
Thhalv10018768m V4MCA7 PAC:20191067 Eutrema salsugineum 357  
Thhalv10018810m V4JU33 PAC:20191068 Eutrema salsugineum 346  
Ciclev10032026m PAC:20804985 Citrus clementina 340  
Ciclev10005360m PAC:20791496 Citrus clementina 340  
Lus10009537 PAC:23145733 Linum usitatissimum 361  
Lus10020357 PAC:23144154 Linum usitatissimum 309  
Potri.013G077000.1 B9I728 PAC:26996105 Populus trichocarpa 349  
Gorai.003G058100.3 A0A0D2NX01 PAC:26800699 Gossypium raimondii 303  
Gorai.003G058100.4 A0A0D2RHD1 PAC:26800700 Gossypium raimondii 300  
Gorai.003G058100.1 A0A0D2QNV2 PAC:26800697 Gossypium raimondii 305  
Gorai.003G058100.2 A0A0D2NX01 PAC:26800698 Gossypium raimondii 303  
Gorai.013G184400.1 PAC:26790937 Gossypium raimondii 345  
33371 I0YWF0 PAC:27388732 Coccomyxa subellipsoidea C-169 261  
58884 I0Z6S8 PAC:27393042 Coccomyxa subellipsoidea C-169 372  
34805 C1MYU6 PAC:27344340 Micromonas pusilla CCMP1545 335  
125925 C1MHQ8 PAC:27345415 Micromonas pusilla CCMP1545 452  
157773 C1MVQ9 PAC:27340672 Micromonas pusilla CCMP1545 449  
75700 C1EAG5 PAC:27404757 Micromonas sp RCC299 315  
59038 C1E7J9 PAC:27401942 Micromonas sp RCC299 369  
61308 C1EC64 PAC:27401320 Micromonas sp RCC299 434  
40586 A4S821 PAC:27417224 Ostreococcus lucimarinus 342  
10269 A4S0U2 PAC:27414275 Ostreococcus lucimarinus 295  
3898 A4RTJ9 PAC:27414971 Ostreococcus lucimarinus 306  
Thecc1EG025566t1 A0A061F000 PAC:27422003 Theobroma cacao 346  

8 Publications

First Author Title Year Journal Volume Pages PubMed ID
            7897657
            12826405
            16225687
            21858014
            9851934
            14682617
            12586887
            11821038