3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0051741 | IPR025774 |
GO:0010189 | IPR025774 |
GO:0032259 | IPR025774 |
Type: | Family | Name: | SAM-dependent methyltransferase gamma-tocopherol (gTMT)-type |
Description: | This entry represents a subgroup of the class I SAM-dependent methyltransferases, including bacterial 2-methyl-6-phytyl-1,4-hydroquinone methyltransferase [] and plant plastid tocopherol O-methyltransferase (also known as g-TMT (gamma-tocopherol methyltransferase)). Tocopherol O-methyltransferase is involved in the synthesis of tocopherol (vitamin E). It methylates gamma- and delta-tocopherol to form beta- and alpha-tocopherol, respectively [, , ].Methyltransferases (EC 2.1.1.-) constitute an important class of enzymes present in every life form. They transfer a methyl group most frequently from S-adenosyl L-methionine (SAM or AdoMet) to a nucleophilic acceptor such as oxygen leading to S-adenosyl-L-homocysteine (AdoHcy) and a methylated molecule [, , ]. All these enzymes have in common a conserved region of about 130 amino acid residues that allow them to bind SAM []. The substrates that are methylated by these enzymes cover virtually every kind of biomolecules ranging from small molecules, to lipids, proteins and nucleic acids [, , ]. Methyltransferase are therefore involved in many essential cellular processes including biosynthesis, signal transduction, protein repair, chromatin regulation and gene silencing [, , ]. More than 230 families of methyltransferases have been described so far, of which more than 220 use SAM as the methyl donor. | Short Name: | MTs_g-TMT |
GO Term | Gene Name |
---|---|
GO:0051741 | IPR025774 |
GO:0010189 | IPR025774 |
GO:0032259 | IPR025774 |