Protein Domain : IPR008158

Type:  Family Name:  Protein translocase SEC61 complex, gamma subunit
Description:  This family is the protein translocase SEC61 complex gamma subunit of the archaeal and eukaryotic type. It does not hit bacterial SecE proteins. Sec61 is required for protein translocation in the endoplasmic reticulum.The Sec61 complex (eukaryotes) or SecY complex (prokaryotes) forms a conserved heterotrimeric integral membrane protein complex and forms a protein-conducting channel that allows polypeptides to be transferred across (or integrated into) the endoplasmic reticulum (eukaryotes) or across the cytoplasmic membrane (prokaryotes) [, ]. This complex is itself a part of a larger translocase heterotrimeric complex composed of alpha, beta and gamma subunits.The channel is a passive conduit for polypeptides. It therefore has to associate with other components that provide a driving force. The partner proteins in bacteria and eukaryotes differ. In bacteria, the translocase complex comprises 7 proteins [], including a chaperone protein (SecB) an ATPase (SecA), an integral membrane complex (SecY, SecE and SecG), and two additional membrane proteins that promote the release of the mature peptide into the periplasm (SecD) and SecF. The SecA ATPase interacts dynamically with the SecYEG integral membrane components to drive the transmembrane movement of newly synthesized preproteins []. In yeast (and probably in all eukaryotes), the full translocase comprises another membrane protein subcomplex (the tetrameric Sec62/63p complex), and the lumenal protein BiP, a member of the Hsp70 family of ATPases. BiP promotes translocation by acting as a molecular ratchet, preventing the polypeptide chain from sliding back into the cytosol []. Short Name:  Translocase_Sec61-g
Paste the following link

1 Child Features

DB identifier Type Name
IPR022943 Family Preprotein translocase subunit SecE

0 Contains

1 Cross References

Identifier
TIGR00327

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0015450 IPR008158
GO:0015031 IPR008158
GO:0016020 IPR008158

3 Ontology Annotations

GO Term Gene Name
GO:0015450 IPR008158
GO:0015031 IPR008158
GO:0016020 IPR008158

1 Parent Features

DB identifier Type Name
IPR001901 Family Protein translocase complex, SecE/Sec61-gamma subunit

822 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
228208 D8RRD8 PAC:15406036 Selaginella moellendorffii 69  
evm.TU.contig_37503.1 PAC:16431042 Carica papaya 69  
evm.model.supercontig_13.108 PAC:16407612 Carica papaya 69  
30147.m014494 B9RAE8 PAC:16820502 Ricinus communis 69  
30190.m010919 B9RBH1 PAC:16823282 Ricinus communis 69  
Cucsa.054090.1 PAC:16954379 Cucumis sativus 69  
Cucsa.054090.2 PAC:16954380 Cucumis sativus 69  
orange1.1g035240m A0A067FL40 PAC:18117577 Citrus sinensis 69  
orange1.1g035234m A0A067FL40 PAC:18117576 Citrus sinensis 69  
AT4G24920.1 P0DI74 PAC:19646978 Arabidopsis thaliana 69  
AT5G50460.1 P0DI75 PAC:19668104 Arabidopsis thaliana 69  
AT3G48570.1 Q9SMP2 PAC:19662400 Arabidopsis thaliana 69  
Thhalv10026733m PAC:20194140 Eutrema salsugineum 69  
Thhalv10010887m V4LPH8 PAC:20206990 Eutrema salsugineum 69  
Thhalv10015212m PAC:20204997 Eutrema salsugineum 69  
Ciclev10017399m V4UDF2 PAC:20818879 Citrus clementina 69  
Ciclev10017403m V4UDF2 PAC:20818880 Citrus clementina 69  
Lus10041552 PAC:23146885 Linum usitatissimum 95  
Lus10035206 PAC:23162370 Linum usitatissimum 69  
Lus10012539 PAC:23143818 Linum usitatissimum 95  
Potri.T042800.1 B9N0X8 PAC:26993181 Populus trichocarpa 73  
Potri.015G097300.1 A9P9W3 PAC:27019500 Populus trichocarpa 69  
Potri.015G097300.2 A9P9W3 PAC:27019501 Populus trichocarpa 69  
Potri.012G098400.1 A9P9P6 PAC:27050148 Populus trichocarpa 69  
Potri.001G329400.1 B9GJU8 PAC:27045895 Populus trichocarpa 69  
Gorai.001G271600.1 A0A0D2QWI5 PAC:26821204 Gossypium raimondii 69  
Gorai.012G086400.1 A0A0D2TL23 PAC:26825427 Gossypium raimondii 69  
Gorai.012G086400.2 A0A0D2TL23 PAC:26825425 Gossypium raimondii 69  
Gorai.012G086400.3 A0A0D2TL23 PAC:26825426 Gossypium raimondii 69  
Gorai.008G206600.1 A0A0D2TTN0 PAC:26812866 Gossypium raimondii 67  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            14661030
            11597451