Protein Domain : IPR019453

Type:  Domain Name:  Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2
Description:  This entry represents a domain found in the vacuolar sorting protein Vps39 and transforming growth factor beta receptor-associated protein Trap1. Vps39, a component of the C-Vps complex, is thought to be required for the fusion of endosomes and other types of transport intermediates with the vacuole [, ]. In Saccharomyces cerevisiae(Baker's yeast), Vps39 has been shown to stimulate nucleotide exchange []. Trap1 plays a role in the TGF-beta/activin signaling pathway. It associates with inactive heteromeric TGF-beta and activin receptor complexes, mainly through the type II receptor, and is released upon activation of signaling [, ]. The precise function of this domain has not been characterised In Vps39 this domain is involved in localisation and in mediating the interactions with Vps11 []. Short Name:  VPS39/TGF_beta_rcpt-assoc_2

0 Child Features

0 Contains

1 Cross References

Identifier
PF10367

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

874 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
442094 D8RQ85 PAC:15407756 Selaginella moellendorffii 1754  
149115 D8RR39 PAC:15408305 Selaginella moellendorffii 974  
evm.model.supercontig_1294.1 PAC:16407592 Carica papaya 371  
evm.model.supercontig_21.90 PAC:16413606 Carica papaya 338  
30077.m000187 B9SBC2 PAC:16817319 Ricinus communis 1005  
29634.m002150 B9S6H6 PAC:16804291 Ricinus communis 972  
Cucsa.201440.1 PAC:16968850 Cucumis sativus 996  
Cucsa.236650.1 PAC:16970501 Cucumis sativus 1011  
orange1.1g001851m PAC:18124580 Citrus sinensis 1004  
orange1.1g003482m PAC:18124582 Citrus sinensis 816  
orange1.1g043572m PAC:18138732 Citrus sinensis 997  
AT4G36630.1 Q8L5Y0 PAC:19646008 Arabidopsis thaliana 1000  
AT1G22860.1 PAC:19652259 Arabidopsis thaliana 961  
Thhalv10024305m V4ML31 PAC:20194642 Eutrema salsugineum 1002  
Thhalv10006692m V4KWV7 PAC:20186150 Eutrema salsugineum 983  
Ciclev10024797m V4UHT4 PAC:20802154 Citrus clementina 1004  
Ciclev10024802m V4RVU0 PAC:20802155 Citrus clementina 971  
Ciclev10014143m V4W785 PAC:20815330 Citrus clementina 997  
Lus10012758 PAC:23148156 Linum usitatissimum 276  
Lus10014310 PAC:23164759 Linum usitatissimum 949  
Lus10026018 PAC:23173251 Linum usitatissimum 948  
Potri.001G081900.1 U5GP59 PAC:27043462 Populus trichocarpa 1004  
Potri.003G148700.2 PAC:26999211 Populus trichocarpa 969  
Potri.003G148700.1 A0A2K2B7B3 PAC:26999210 Populus trichocarpa 1002  
Potri.005G123000.1 A0A2K2AFR6 PAC:27029675 Populus trichocarpa 1008  
Potri.007G025700.3 A0A2K1ZN90 PAC:27016612 Populus trichocarpa 1001  
Potri.007G025700.1 A0A2K1ZN90 PAC:27016611 Populus trichocarpa 1001  
Potri.007G025700.2 PAC:27016613 Populus trichocarpa 953  
Gorai.003G015100.1 A0A0D2NUW9 PAC:26799198 Gossypium raimondii 983  
Gorai.007G203400.2 A0A0D2QWI9 PAC:26783751 Gossypium raimondii 1000  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9111041
            1493335
            11062257
            9545258
            11278302