Protein Domain : IPR001354

Type:  Family Name:  Mandelate racemase/muconate lactonizing enzyme/methylaspartate ammonia-lyase
Description:  This entry includes both the mandelate racemase/muconate lactonizing enzyme family, and the methylaspartate ammonia-lyase family. Both families belong to the enolase superfamily []. Mandelate racemase () and muconate lactonizing enzyme () are two bacterial enzymes involved in aromatic acid catabolism. They catalyse mechanistically distinct reactions yet they are related at the level of their primary, quaternary (homooctamer) and tertiary structures [, ]. Other members of this family include:D-glucarate dehydrataseD-xylonate dehydratase []Galactarate dehydratase/L-talarate dehydrataseD-arabinonate dehydrataseD-galactonate dehydratase []D-gluconate dehydrataseL-fuconate dehydrataseD-tartrate dehydrataseL-rhamnonate dehydratase []2-succinyl-6-hydroxy-2,4-cyclohexa-diene-1-carboxylic acidO-succinylbenzoic acidL-Ala-D/L-Glu epimeraseMethylaspartate ammonia-lyase () is involved in the methylaspartate cycle []. Short Name:  MR/MLE/MAL
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7 Child Features

DB identifier Type Name
IPR010196 Family o-succinylbenzoate synthase, MenC type1
IPR010197 Family o-succinylbenzoate synthase, MenC type 2
IPR006395 Family Methylaspartate ammonia-lyase
IPR017653 Family Glucarate dehydratase
IPR013370 Family Muconate/chloromuconate cycloisomerase
IPR023444 Family L-rhamnonate dehydratase
IPR023592 Family D-galactonate dehydratase

2 Contains

DB identifier Type Name
IPR013342 Domain Mandelate racemase/muconate lactonizing enzyme, C-terminal
IPR018110 Conserved_site Mandelate racemase/muconate lactonizing enzyme, conserved site

1 Cross References

Identifier
PTHR13794

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0003824 IPR001354
GO:0008152 IPR001354

2 Ontology Annotations

GO Term Gene Name
GO:0003824 IPR001354
GO:0008152 IPR001354

0 Parent Features

593 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
413825 D8RQB9 PAC:15417472 Selaginella moellendorffii 378  
98948 D8RQC4 PAC:15417456 Selaginella moellendorffii 374  
evm.model.supercontig_170.33 PAC:16410853 Carica papaya 437  
evm.model.supercontig_3.467 PAC:16416776 Carica papaya 424  
29747.m001090 B9SFX6 PAC:16807756 Ricinus communis 375  
30976.m000026 B9TJ90 PAC:16824739 Ricinus communis 162  
33012.m000014 B9TH26 PAC:16825656 Ricinus communis 368  
45331.m000013 B9TPI5 PAC:16827793 Ricinus communis 209  
46618.m000014 B9TN35 PAC:16827905 Ricinus communis 288  
55742.m000013 B9TP22 PAC:16828859 Ricinus communis 297  
29586.m000627 B9SQ11 PAC:16803206 Ricinus communis 453  
Cucsa.088030.1 PAC:16956945 Cucumis sativus 466  
Cucsa.088030.2 PAC:16956946 Cucumis sativus 449  
Cucsa.111220.1 PAC:16960008 Cucumis sativus 432  
Cucsa.111220.2 PAC:16960009 Cucumis sativus 410  
orange1.1g014285m A0A067FAS2 PAC:18131049 Citrus sinensis 427  
orange1.1g013681m A0A067FJ69 PAC:18131048 Citrus sinensis 438  
orange1.1g015289m A0A067E7G1 PAC:18110013 Citrus sinensis 409  
orange1.1g014886m A0A067E417 PAC:18110011 Citrus sinensis 416  
orange1.1g015161m A0A067E3M4 PAC:18110012 Citrus sinensis 412  
AT3G18270.1 Q94K39 PAC:19664959 Arabidopsis thaliana 410  
Thhalv10020846m V4M6X6 PAC:20181542 Eutrema salsugineum 407  
Thhalv10022164m V4LCD3 PAC:20182776 Eutrema salsugineum 382  
Ciclev10011789m V4UW71 PAC:20796487 Citrus clementina 428  
Ciclev10024630m V4TQX2 PAC:20809995 Citrus clementina 151  
Ciclev10024623m V4TVS9 PAC:20809993 Citrus clementina 409  
Ciclev10024642m V4T6F1 PAC:20809994 Citrus clementina 187  
Ciclev10024636m V4VRY4 PAC:20809992 Citrus clementina 412  
Lus10020434 PAC:23139583 Linum usitatissimum 383  
Lus10007062 PAC:23153229 Linum usitatissimum 408  

7 Publications

First Author Title Year Journal Volume Pages PubMed ID
            2215699
            8256284
            18754693
            324806
            19584053
            15581566
            22005738