Type: | Family | Name: | Biogenesis of lysosome-related organelles complex 1 subunit 1 |
Description: | GCN5L1 (general control of amino acid synthesis 5-like 1), also known as BLOC1S1 (biogenesis of lysosome-related organelles complex 1 subunit 1). It is a component of the BLOC-1 complex, a complex required for normal biogenesis of lysosome-related organelles []. GCN5L1 has been identified as a critical component of the mitochondrial protein acetylation programme [, ]. It acts as a nutrient-sensing regulator that controls mitochondrial content through coordinated regulation of mitochondrial biogenesis and autophagy []. | Short Name: | BLOC1S1 |