Protein Domain : IPR005747

Type:  Family Name:  Endonuclease MutS2
Description:  The MutS family of proteins is named after the Salmonella typhimurium MutS protein involved in mismatch repair. Homologues of MutS have been found in many species including eukaryotes (MSH 1, 2, 3, 4, 5, and 6 proteins), archaea and bacteria, and together these proteins have been grouped into the MutS family. Although many of these proteins have similar activities to the E. coli MutS, there is significant diversity of function among the MutS family members. Inter-species homologues may have arisen through frequent ancient horizontal gene transfer of MutS (and MutL) from bacteria to archaea and eukaryotes via endosymbiotic ancestors of mitochondria and chloroplasts []. This entry represents endonuclease MutS2. MutS2 is a paralogue of MutS and is not involved in DNA mismatch repair but in the suppression of homologous recombination [, , , ]. It may therefore have a key role in the control of bacterial genetic diversity. Short Name:  MutS2
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0 Child Features

3 Contains

DB identifier Type Name
IPR000432 Domain DNA mismatch repair protein MutS, C-terminal
IPR002625 Domain Smr domain
IPR007696 Domain DNA mismatch repair protein MutS, core

4 Cross Referencess

Identifier
PTHR11361:SF14
PIRSF005814
TIGR01069
MF_00092

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0004519 IPR005747
GO:0016887 IPR005747
GO:0030983 IPR005747
GO:0045910 IPR005747

4 Ontology Annotations

GO Term Gene Name
GO:0004519 IPR005747
GO:0016887 IPR005747
GO:0030983 IPR005747
GO:0045910 IPR005747

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
141299 D8QVD5 PAC:15408170 Selaginella moellendorffii 825  
evm.model.supercontig_27.54 PAC:16415675 Carica papaya 756  
29851.m002400 B9RZ79 PAC:16811427 Ricinus communis 873  
Cucsa.126600.1 PAC:16961948 Cucumis sativus 883  
orange1.1g004609m A0A067GBB5 PAC:18114828 Citrus sinensis 742  
orange1.1g006974m A0A067GKS3 PAC:18114829 Citrus sinensis 623  
orange1.1g007057m A0A067GKG0 PAC:18114830 Citrus sinensis 620  
orange1.1g003258m A0A067G8L4 PAC:18114826 Citrus sinensis 835  
orange1.1g004463m A0A067G8F1 PAC:18114827 Citrus sinensis 752  
orange1.1g003142m PAC:18130122 Citrus sinensis 844  
orange1.1g003163m PAC:18130123 Citrus sinensis 843  
AT5G54090.1 F4JYU0 PAC:19672029 Arabidopsis thaliana 796  
AT1G65070.2 Q9SS53 PAC:19651521 Arabidopsis thaliana 876  
AT1G65070.1 F4I9U0 PAC:19651522 Arabidopsis thaliana 857  
Thhalv10012724m V4LKW7 PAC:20204188 Eutrema salsugineum 802  
Thhalv10022461m V4N1B1 PAC:20202488 Eutrema salsugineum 890  
Ciclev10018840m V4TS07 PAC:20807443 Citrus clementina 844  
Ciclev10019235m V4VNN0 PAC:20807444 Citrus clementina 648  
Ciclev10014268m V4TPW2 PAC:20819265 Citrus clementina 835  
Lus10025647 PAC:23145037 Linum usitatissimum 918  
Lus10015589 PAC:23145914 Linum usitatissimum 895  
Lus10032917 PAC:23160392 Linum usitatissimum 865  
Lus10018187 PAC:23145236 Linum usitatissimum 917  
Potri.012G005000.1 A0A2K1Y6T9 PAC:27049197 Populus trichocarpa 843  
Potri.012G005000.2 A0A3N7FSP0 PAC:27049198 Populus trichocarpa 842  
Potri.012G011200.2 PAC:27048907 Populus trichocarpa 627  
Potri.012G011200.1 PAC:27048906 Populus trichocarpa 683  
Potri.004G041900.1 B9H2W4 PAC:26991791 Populus trichocarpa 908  
Potri.004G041900.2 PAC:26991792 Populus trichocarpa 843  
Potri.011G051100.1 B9N3E3 PAC:27002069 Populus trichocarpa 120  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            17965091
            18838375
            15629722
            15866941
            15113836