1 Parent Features
DB identifier | Type | Name |
---|---|---|
IPR011991 | Domain | Winged helix-turn-helix DNA-binding domain |
Type: | Domain | Name: | Cdc6, C-terminal domain |
Description: | The C-terminal domain of cell division control protein 6 (CDC6) assumes a winged helix fold, with a five alpha-helical bundle (alpha15-alpha19) structure, backed on one side by three beta strands (beta6-beta8). It has been shown that this domain acts as a DNA-localisation factor, however its exact function is, as yet, unknown. Putative functions include: (1) mediation of protein-protein interactions and (2) regulation of nucleotide binding and hydrolysis. Mutagenesis studies have shown that this domain is essential for appropriate CDC6 activity []. | Short Name: | Cdc6_C_dom |
DB identifier | Type | Name |
---|---|---|
IPR011991 | Domain | Winged helix-turn-helix DNA-binding domain |