| Type: | Family | Name: | AB-hydrolase ABHD1/2/3 |
| Description: | This entry represents a group of abhydrolase domain-containing proteins, including mammalian ABHD1/2/3 and budding yeast Eht1 and Eeb1.Human ABHD3 is a phospholipase that may play a role in phospholipids remodeling. It may selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position []. Mouse ABHD2 may play a role in smooth muscle cells migration []. Yeast Eht1 and its paralogue, Eeb1, are Acyl-coenzymeA:ethanol O-acyltransferases involved in medium-chain fatty acid ethyl ester biosynthesis during fermentation []. This entry also includes bacterial putative esterases, such as yheT from E. coli. | Short Name: | ABHD1/2/3 |
