3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0015103 | IPR004706 |
GO:0015297 | IPR004706 |
GO:0016021 | IPR004706 |
1 Parent Features
DB identifier | Type | Name |
---|---|---|
IPR002657 | Family | Bile acid:sodium symporter/arsenical resistance protein Acr3 |
Type: | Family | Name: | Arsenical-resistance protein Acr3 |
Description: | Members of the ACR3 family of arsenite (As(III)) permeases confer resistance to arsenic by extrusion from cells []. They exist in prokaryotes and eukaryotes (lower plants and fungi) [, ]. The ACR3 permeases have ten-transmembrane span topology []. Corynebacterium glutamicum has three Acr3 proteins, CgAcr3-1, CgAcr3-2, and CgAcr3-3. CgAcr3-1 is thought to be an antiporter that catalyses arsenite-proton exchange [].The Shewanella oneidensis Acr3 is not able to transport As(III) and confers resistance only to arsenate (As(V)) [], whereas the Acr3 orthologue from Synechocystis mediates tolerance to As(III), As(V) and antimonite (Sb(III)) [].In budding yeast, overexpression of the Acr3 gene confers an arsenite- but not an arsenate-resistance phenotype []. Saccharomyces cerevisiae Acr3 is a plasma membrane metalloid/H+ antiporter that transports arsenite and antimonite []. | Short Name: | Arsenical-R_Acr3 |
GO Term | Gene Name |
---|---|
GO:0015103 | IPR004706 |
GO:0015297 | IPR004706 |
GO:0016021 | IPR004706 |
DB identifier | Type | Name |
---|---|---|
IPR002657 | Family | Bile acid:sodium symporter/arsenical resistance protein Acr3 |