Protein Domain : IPR006312

Type:  Family Name:  Sec-independent protein translocase protein TatA/E
Description:  Translocation of proteins across the two membranes of Gram-negative bacteria can be carried out via a number of routes. Most proteins marked for export carry a secretion signal at their N terminus, and are secreted by the general secretory pathway. The signal peptide is cleaved as they pass through the outer membrane. Other secretion systems include the type III system found in a select group of Gram-negative plant and animal pathogens, and the CagA system of Helicobacter pylori[].In some bacterial species, however, there exists a system that operates independently of the Sec pathway []. It selectively translocates periplasmic-bound molecules that are synthesised with, or are in close association with, "partner" proteins bearing an (S/T)RRXFLK twin arginine motif at the N terminus. The pathway is therefore termed the Twin-Arginine Translocation or TAT system. Surprisingly, the four components that make up the TAT system are structurally and mechanistically related to a pH-dependent import system in plant chloroplast thylakoid membranes []. Thegene products responsible for the Sec-independent pathway are called TatA, TatB, TatC and TatE.TatA and TatE are highly related proteins and appear to overlap in functionality []. Translocation occurred in single mutants of either TatA or TatE, though much less efficiently, but double mutants showed no detectable translocation. Short Name:  TatA/E

1 Child Features

DB identifier Type Name
IPR024905 Family Sec-independent protein translocase protein TatE

0 Contains

2 Cross Referencess

Identifier
TIGR01411
MF_00236

0 Found In

5 GO Annotations

GO Term Gene Name
GO:0008565 IPR006312
GO:0009306 IPR006312
GO:0015031 IPR006312
GO:0005886 IPR006312
GO:0016021 IPR006312

5 Ontology Annotations

GO Term Gene Name
GO:0008565 IPR006312
GO:0009306 IPR006312
GO:0015031 IPR006312
GO:0005886 IPR006312
GO:0016021 IPR006312

1 Parent Features

DB identifier Type Name
IPR003369 Family Sec-independent protein translocase protein TatA/B/E

803 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
36641 D8TAT9 PAC:15410823 Selaginella moellendorffii 75  
267974 D8RZ40 PAC:15415189 Selaginella moellendorffii 156  
evm.model.supercontig_107.83 PAC:16405391 Carica papaya 253  
evm.model.supercontig_117.91 PAC:16406453 Carica papaya 154  
30169.m006234 B9RIV4 PAC:16821037 Ricinus communis 255  
29598.m000466 B9SZ75 PAC:16803461 Ricinus communis 149  
Cucsa.289100.1 A0A0A0LWL1 PAC:16975166 Cucumis sativus 158  
orange1.1g031919m A0A067E104 PAC:18106556 Citrus sinensis 150  
orange1.1g023111m A0A067EDJ1 PAC:18126998 Citrus sinensis 287  
orange1.1g023222m A0A067E9T8 PAC:18126999 Citrus sinensis 285  
orange1.1g027491m A0A067ELZ7 PAC:18127001 Citrus sinensis 222  
orange1.1g027443m A0A067EL87 PAC:18127000 Citrus sinensis 223  
AT5G28750.1 Q9LKU2 PAC:19666479 Arabidopsis thaliana 147  
AT5G52440.1 Q9XH75 PAC:19672573 Arabidopsis thaliana 260  
Thhalv10005085m V4MLJ3 PAC:20200321 Eutrema salsugineum 145  
Ciclev10002770m V4SEX5 PAC:20789039 Citrus clementina 150  
Ciclev10005655m V4RLY5 PAC:20792403 Citrus clementina 263  
Lus10015910 PAC:23143774 Linum usitatissimum 199  
Lus10039254 PAC:23175488 Linum usitatissimum 286  
Lus10006588 PAC:23162688 Linum usitatissimum 154  
Lus10027499 PAC:23144572 Linum usitatissimum 666  
Potri.015G147100.1 B9IDB3 PAC:27019728 Populus trichocarpa 259  
Potri.015G147100.2 PAC:27019729 Populus trichocarpa 213  
Potri.012G144300.1 A0A2K1YDK6 PAC:27050577 Populus trichocarpa 264  
Potri.005G053400.3 PAC:27031164 Populus trichocarpa 180  
Potri.005G053400.2 PAC:27031163 Populus trichocarpa 192  
Potri.005G053400.1 PAC:27031162 Populus trichocarpa 211  
Potri.013G040900.2 B9I5F5 PAC:26993817 Populus trichocarpa 149  
Potri.013G040900.1 B9I5F5 PAC:26993816 Populus trichocarpa 149  
Gorai.013G200900.1 A0A0D2VHZ3 PAC:26790614 Gossypium raimondii 157  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9649434
            10652088