Protein Domain : IPR016072

Type:  Domain Name:  SKP1 component, dimerisation
Description:  SKP1 (together with SKP2) was identified as an essential component of the cyclin A-CDK2 S phase kinase complex []. It was found to bind several F-box containing proteins (e.g., Cdc4, Skp2, cyclin F) and to be involved in the ubiquitin protein degradation pathway. A yeast homologue of SKP1 (P52286) was identified in the centromere bound kinetochore complex [] and is also involved in the ubiquitin pathway []. In Dictyostelium discoideum(Slime mold) FP21 was shown to be glycosylated in the cytosol and has homology to SKP1 [].This entry represents a dimerisation domain found at the C-terminal of SKP1 proteins [], as well as in subunit D of the centromere DNA-binding protein complex Cbf3 []. This domain is multi-helical in structure, and consists of an interlocked herterodimer in F-box proteins. Short Name:  Skp1_comp_dimer

0 Child Features

0 Contains

2 Cross Referencess

Identifier
PF01466
SSF81382

1 Found In

DB identifier Type Name
IPR016897 Family S-phase kinase-associated protein 1

1 GO Annotation

GO Term Gene Name
GO:0006511 IPR016072

1 Ontology Annotations

GO Term Gene Name
GO:0006511 IPR016072

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
430426 D8T9D5 PAC:15420037 Selaginella moellendorffii 258  
98727 D8RNY6 PAC:15415929 Selaginella moellendorffii 137  
271223 D8S106 PAC:15421534 Selaginella moellendorffii 157  
115864 D8SFP2 PAC:15402811 Selaginella moellendorffii 229  
evm.model.supercontig_107.78 PAC:16405385 Carica papaya 360  
evm.model.supercontig_11.11 PAC:16405596 Carica papaya 363  
evm.model.supercontig_138.4 PAC:16408475 Carica papaya 187  
evm.model.supercontig_20.87 PAC:16413116 Carica papaya 467  
evm.model.supercontig_20.89 PAC:16413118 Carica papaya 174  
evm.model.supercontig_26.289 PAC:16415237 Carica papaya 157  
evm.model.supercontig_34.34 PAC:16417978 Carica papaya 168  
evm.model.supercontig_37.218 PAC:16418679 Carica papaya 169  
evm.model.supercontig_37.216 PAC:16418677 Carica papaya 195  
evm.model.supercontig_37.220 PAC:16418682 Carica papaya 169  
evm.model.supercontig_53.112 PAC:16422173 Carica papaya 188  
evm.model.supercontig_6.295 PAC:16423481 Carica papaya 155  
29819.m000081 B9T4M1 PAC:16809639 Ricinus communis 144  
30146.m003614 B9RQQ0 PAC:16819734 Ricinus communis 172  
30169.m006242 B9RIW2 PAC:16821045 Ricinus communis 378  
30169.m006304 B9RHZ0 PAC:16821105 Ricinus communis 173  
30170.m014264 B9R8D3 PAC:16822097 Ricinus communis 157  
30170.m014265 B9R8D4 PAC:16822098 Ricinus communis 157  
30174.m008613 B9RDT2 PAC:16822259 Ricinus communis 359  
30205.m001614 B9RSN9 PAC:16823990 Ricinus communis 168  
34425.m000015 B9TGY7 PAC:16826219 Ricinus communis 158  
28962.m000447 B9SYT1 PAC:16802046 Ricinus communis 161  
Cucsa.322790.1 PAC:16977830 Cucumis sativus 155  
Cucsa.393980.1 PAC:16983120 Cucumis sativus 229  
Cucsa.193080.4 PAC:16968045 Cucumis sativus 359  
Cucsa.193080.1 PAC:16968042 Cucumis sativus 385  

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10205047
            8670864
            7852383
            9390558
            12553912
            11099048