3 Ontology Annotations
| GO Term | Gene Name |
|---|---|
| GO:0004812 | IPR000738 |
| GO:0005524 | IPR000738 |
| GO:0006418 | IPR000738 |
| Type: | Domain | Name: | WHEP-TRS domain |
| Description: | A conserved domain of 46 amino acids, called WHEP-TRS has been shown [] to exist in a number of higher eukaryote aminoacyl-transfer RNA synthetases. This domain is present one to six times in the several enzymes. There are three copies in mammalian multifunctional aminoacyl-tRNA synthetase in a region that separates the N-terminal glutamyl-tRNA synthetase domain from the C-terminal prolyl-tRNA synthetase domain, and six copies in the intercatalytic region of the Drosophila enzyme. The domain is found at the N-terminal extremity of the mammalian tryptophanyl-tRNA synthetase and histidyl-tRNA synthetase, and the mammalian, insect, nematode and plant glycyl- tRNA synthetases []. The structure of a human WHEP-TRS domain has been solved and consists of two helices arranged in a helix-turn-helix []. The WHEP-TRS domain may play a role in the association of tRNA-synthetases into multienzyme complexes []. | Short Name: | WHEP-TRS_dom |
| GO Term | Gene Name |
|---|---|
| GO:0004812 | IPR000738 |
| GO:0005524 | IPR000738 |
| GO:0006418 | IPR000738 |
