Protein Domain : IPR016655

Type:  Family Name:  Prefoldin subunit 3
Description:  Prefoldin subunit 3 (PFD3, also known as VBP-1) is part of the heteromeric co-chaperone complex, which delivers unfolded proteins to cytosolic chaperonin and acts as a cofactor. PFD3 binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. It binds to nascent polypeptide chain and promotes folding []. In fruit flies PFD3 (also known as mgr) interacts with von Hippel Lindau protein (Vhl) and betaTub56D/tubulin beta-1 chain. It is required for tubulin stability and spindle and centrosome formation in cooperation with Vhl []. Short Name:  PFD3
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0 Child Features

0 Contains

2 Cross Referencess

Identifier
PTHR12409
PIRSF016396

0 Found In

2 GO Annotations

GO Term Gene Name
GO:0006457 IPR016655
GO:0016272 IPR016655

2 Ontology Annotations

GO Term Gene Name
GO:0006457 IPR016655
GO:0016272 IPR016655

1 Parent Features

DB identifier Type Name
IPR004127 Family Prefoldin alpha-like

431 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
171147 D8RFY6 PAC:15406591 Selaginella moellendorffii 190  
evm.model.supercontig_9.38 PAC:16428290 Carica papaya 196  
29889.m003320 B9RZT0 PAC:16812267 Ricinus communis 185  
orange1.1g031875m A0A067G983 PAC:18109836 Citrus sinensis 151  
orange1.1g030290m A0A067G0P4 PAC:18109835 Citrus sinensis 180  
orange1.1g028810m A0A067FX87 PAC:18109833 Citrus sinensis 203  
orange1.1g029196m A0A067FX38 PAC:18109834 Citrus sinensis 197  
AT5G49510.2 P57741 PAC:19668441 Arabidopsis thaliana 195  
AT5G49510.1 P57741 PAC:19668440 Arabidopsis thaliana 195  
Thhalv10004957m V4KY58 PAC:20199037 Eutrema salsugineum 195  
Ciclev10005911m V4RFE1 PAC:20790926 Citrus clementina 203  
Lus10011145 PAC:23167521 Linum usitatissimum 187  
Lus10037784 PAC:23167144 Linum usitatissimum 179  
Lus10017066 PAC:23167473 Linum usitatissimum 189  
Lus10043046 PAC:23168372 Linum usitatissimum 187  
Potri.010G147600.1 A0A2K1YU60 PAC:26981099 Populus trichocarpa 192  
Potri.008G103400.1 B9HIM0 PAC:27035980 Populus trichocarpa 196  
Potri.008G103400.2 PAC:27035981 Populus trichocarpa 181  
Gorai.002G030800.1 A0A0D2Q754 PAC:26793966 Gossypium raimondii 196  
Gorai.002G030800.2 A0A0D2Q754 PAC:26793967 Gossypium raimondii 196  
Gorai.002G030800.3 A0A0D2QZU7 PAC:26793968 Gossypium raimondii 179  
61549 I0Z3V8 PAC:27390123 Coccomyxa subellipsoidea C-169 108  
214093 C1N5T8 PAC:27342197 Micromonas pusilla CCMP1545 159  
88734 C1EID8 PAC:27400830 Micromonas sp RCC299 168  
39093 A4S5A7 PAC:27417128 Ostreococcus lucimarinus 157  
Thecc1EG021398t1 A0A061EPK0 PAC:27454734 Theobroma cacao 193  
Migut.N00036.1.p A0A022S2J3 PAC:28926125 Mimulus guttatus 186  
Migut.N00036.2.p A0A022S2J3 PAC:28926126 Mimulus guttatus 186  
Araha.15845s0001.1.p PAC:28839063 Arabidopsis halleri 195  
Cagra.3135s0001.1.p PAC:28893678 Capsella grandiflora 195  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9630229
            22451918