Type: | Domain | Name: | Jacalin-like lectin domain |
Description: | This entry represents a jacalin-like mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some proteins with this domain stimulate distinct T- and B- cell functions, such as the plant lectin jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein. Proteins containing this domain include:Jacalin, a tetrameric plant seed lectin and agglutinin from Artocarpus heterophyllus(jackfruit), which is specific for galactose [].Artocarpin, a tetrameric plant seed lectin from A. heterophyllus [].Lectin MPA, a tetrameric plant seed lectin and agglutinin from Maclura pomifera(Osage orange), [].Heltuba lectin, a plant seed lectin and agglutinin from Helianthus tuberosus(Jerusalem artichoke) [].Agglutinin from Calystegia sepium(Hedge bindweed) [].Griffithsin, an anti-viral lectin from red algae (Griffithsia species) []. | Short Name: | Jacalin-like_lectin_dom |