Protein Domain : IPR020594

Type:  Family Name:  Ribosomal protein L9, bacteria/chloroplast
Description:  Ribosomes are the particles that catalyse mRNA-directed protein synthesis in all organisms. The codons of the mRNA are exposed on the ribosome to allow tRNA binding. This leads to the incorporation of amino acids into the growing polypeptide chain in accordance with the genetic information. Incoming amino acid monomers enter the ribosomal A site in the form of aminoacyl-tRNAs complexed with elongation factor Tu (EF-Tu) and GTP. The growing polypeptide chain, situated in the P site as peptidyl-tRNA, is then transferred to aminoacyl-tRNA and the new peptidyl-tRNA, extended by one residue, is translocated to the P site with the aid the elongation factor G (EF-G) and GTP as the deacylated tRNA is released from the ribosome through one or more exit sites [, ]. About 2/3 of the mass of the ribosome consists of RNA and 1/3 of protein. The proteins are named in accordance with the subunit of the ribosome which they belong to - the small (S1 to S31) and the large (L1 to L44). Usually they decorate the rRNA cores of the subunits. Many ribosomal proteins, particularly those of the large subunit, are composed of a globular, surfaced-exposed domain with long finger-like projections that extend into the rRNA core to stabilise its structure. Most of the proteins interact with multiple RNA elements, often from different domains. In the large subunit, about 1/3 of the 23S rRNA nucleotides are at least in van der Waal's contact with protein, and L22 interacts with all six domains of the 23S rRNA. Proteins S4 and S7, which initiate assembly of the 16S rRNA, are located at junctions of five and four RNA helices, respectively. In this way proteins serve to organise and stabilise the rRNA tertiary structure. While the crucial activities of decoding and peptide transfer are RNA based, proteins play an active role in functions that may have evolved to streamline the process of protein synthesis. In addition to their function in the ribosome, many ribosomal proteins have some function 'outside' the ribosome [, ].Ribosomal protein L9 is one of the proteins from the large ribosomal subunit. In Escherichia coli, L9 is known to bind directly to the 23S rRNA. It belongs to a family of ribosomal proteins grouped on the basis of sequence similarities [].The crystal structure of Bacillus stearothermophilusL9 shows the 149-residue protein comprises two globular domains connected by a rigid linker []. Each domain contains an rRNA binding site, and the protein functions as astructural protein in the large subunit of the ribosome. The C-terminal domain consists of two loops, an alpha-helix and a three-stranded mixed parallel, anti-parallel beta-sheet packed against the central alpha-helix. The long central alpha-helix is exposed to solvent in the middle and participates in thehydrophobic cores of the two domains at both ends. This entry represents ribosomal L9 proteins found in bacteria and plastids, but not in mitochondria. Short Name:  Ribosomal_L9_bac/chp

0 Child Features

3 Contains

DB identifier Type Name
IPR020069 Domain Ribosomal protein L9, C-terminal
IPR020070 Domain Ribosomal protein L9, N-terminal
IPR009027 Domain Ribosomal protein L9/RNase H1, N-terminal

2 Cross Referencess

Identifier
TIGR00158
MF_00503

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0003735 IPR020594
GO:0006412 IPR020594
GO:0005622 IPR020594
GO:0005840 IPR020594

4 Ontology Annotations

GO Term Gene Name
GO:0003735 IPR020594
GO:0006412 IPR020594
GO:0005622 IPR020594
GO:0005840 IPR020594

1 Parent Features

DB identifier Type Name
IPR000244 Family Ribosomal protein L9

471 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
270732 D8RC52 PAC:15422510 Selaginella moellendorffii 194  
evm.model.supercontig_47.1 PAC:16420610 Carica papaya 196  
29589.m001267 B9SCL1 PAC:16803308 Ricinus communis 210  
Cucsa.207500.2 A0A0A0LXN8 PAC:16969244 Cucumis sativus 198  
Cucsa.207500.3 A0A0A0LXN8 PAC:16969245 Cucumis sativus 198  
Cucsa.207500.5 PAC:16969247 Cucumis sativus 194  
Cucsa.207500.1 PAC:16969243 Cucumis sativus 246  
orange1.1g031586m A0A067FAS6 PAC:18104302 Citrus sinensis 157  
orange1.1g033584m A0A067FA01 PAC:18104304 Citrus sinensis 116  
orange1.1g029171m A0A067F2G6 PAC:18104300 Citrus sinensis 198  
orange1.1g029153m A0A067F2G6 PAC:18104301 Citrus sinensis 198  
AT3G44890.1 P25864 PAC:19663947 Arabidopsis thaliana 197  
Thhalv10023194m V4MDS2 PAC:20202432 Eutrema salsugineum 100  
Thhalv10002672m V4LCQ2 PAC:20196486 Eutrema salsugineum 197  
Thhalv10002671m V4LCQ2 PAC:20196487 Eutrema salsugineum 197  
Ciclev10029220m V4UEF5 PAC:20813783 Citrus clementina 227  
Ciclev10029219m V4UEF5 PAC:20813782 Citrus clementina 227  
Lus10041346 PAC:23179733 Linum usitatissimum 198  
Lus10037372 PAC:23152454 Linum usitatissimum 198  
Potri.004G217000.2 A9PI62 PAC:26991306 Populus trichocarpa 198  
Potri.004G217000.1 A9PI62 PAC:26991307 Populus trichocarpa 198  
Potri.004G217000.3 A9PI62 PAC:26991308 Populus trichocarpa 198  
Gorai.009G090100.2 A0A0D2TM28 PAC:26767768 Gossypium raimondii 194  
Gorai.009G090100.3 A0A0D2TM28 PAC:26767767 Gossypium raimondii 194  
Gorai.009G090100.4 A0A0D2QC43 PAC:26767770 Gossypium raimondii 139  
Gorai.009G090100.1 A0A0D2TM28 PAC:26767769 Gossypium raimondii 194  
17670 I0YTE2 PAC:27391841 Coccomyxa subellipsoidea C-169 111  
159224 PAC:27338834 Micromonas pusilla CCMP1545 178  
62813 C1EF10 PAC:27404883 Micromonas sp RCC299 196  
29830 A4RTL6 PAC:27414548 Ostreococcus lucimarinus 195  

5 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11297922
            11290319
            11114498
            8306963
            12051860