3 Ontology Annotations
GO Term | Gene Name |
---|---|
GO:0016491 | IPR012171 |
GO:0006629 | IPR012171 |
GO:0016021 | IPR012171 |
Type: | Family | Name: | Fatty acid desaturase |
Description: | This entry includes fatty acid desaturase family members from bacteria, fungi, plants and animals. It also includes cytochrome b5-related protein from flies [] and linoleoyl-CoA desaturase from Synechocystis []. Proteins in this family contain the fatty acid desaturase domain (). Some eukaryotic fatty acid desaturases, including human FADS1 and FADS2, are fusion proteins containing an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion []. Some proteins in this entry do not have the cytochrome b5-like domain. Three human fatty acid desaturase genes have been identified, acid desaturase 1-3 (FADS1-3). FADS1 and FADS2 encode delta-5 desaturase (D5D) and delta-6 desaturase (D6D) respectively. They are membrane-bound enzymes that catalyse the rate-limiting formation of endogenous long-chain polyunsaturated fatty acid (PUFA). The function of the FADS3 product is not clear []. | Short Name: | Fatty_acid_desaturase |
GO Term | Gene Name |
---|---|
GO:0016491 | IPR012171 |
GO:0006629 | IPR012171 |
GO:0016021 | IPR012171 |