| Type: | Domain | Name: | FACT complex subunit Spt16p/Cdc68p |
| Description: | Proteins in this entry are subunits the FACT complex; the FACT complex is a stable heterodimer in Saccharomyces cerevisiae(Baker's yeast) comprising Spt16p and Pob3p. The complex plays a role in transcription initiation and promotes binding of TATA-binding protein (TBP) to a TATA box in chromatin []; it also facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilising and then reassembling nucleosome structure [, ]. The proteins in this entry are non-peptidase homologues belonging to MEROPS peptidase family M24 (clan MG). | Short Name: | FACT_Spt16p |
