Protein Domain : IPR000289

Type:  Family Name:  Ribosomal protein S28e
Description:  Ribosomes are the particles that catalyse mRNA-directed protein synthesis in all organisms. The codons of the mRNA are exposed on the ribosome to allow tRNA binding. This leads to the incorporation of amino acids into the growing polypeptide chain in accordance with the genetic information. Incoming amino acid monomers enter the ribosomal A site in the form of aminoacyl-tRNAs complexed with elongation factor Tu (EF-Tu) and GTP. The growing polypeptide chain, situated in the P site as peptidyl-tRNA, is then transferred to aminoacyl-tRNA and the new peptidyl-tRNA, extended by one residue, is translocated to the P site with the aid the elongation factor G (EF-G) and GTP as the deacylated tRNA is released from the ribosome through one or more exit sites [, ]. About 2/3 of the mass of the ribosome consists of RNA and 1/3 of protein. The proteins are named in accordance with the subunit of the ribosome which they belong to - the small (S1 to S31) and the large (L1 to L44). Usually they decorate the rRNA cores of the subunits. Many ribosomal proteins, particularly those of the large subunit, are composed of a globular, surfaced-exposed domain with long finger-like projections that extend into the rRNA core to stabilise its structure. Most of the proteins interact with multiple RNA elements, often from different domains. In the large subunit, about 1/3 of the 23S rRNA nucleotides are at least in van der Waal's contact with protein, and L22 interacts with all six domains of the 23S rRNA. Proteins S4 and S7, which initiate assembly of the 16S rRNA, are located at junctions of five and four RNA helices, respectively. In this way proteins serve to organise and stabilise the rRNA tertiary structure. While the crucial activities of decoding and peptide transfer are RNA based, proteins play an active role in functions that may have evolved to streamline the process of protein synthesis. In addition to their function in the ribosome, many ribosomal proteins have some function 'outside' the ribosome [, ].A number of eukaryotic and archaebacterial ribosomal proteins can be grouped on the basis of sequence similarities. Examples are:Mammalian S28 []Plant S28 []Fungi S33 []Archaebacterial S28e.These proteins have from 64 to 78 amino acids and a highly conserved C-terminal region. Short Name:  Ribosomal_S28e
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0 Child Features

1 Contains

DB identifier Type Name
IPR012340 Domain Nucleic acid-binding, OB-fold

4 Cross Referencess

Identifier
PTHR10769
PF01200
PD005541
MF_00292

0 Found In

4 GO Annotations

GO Term Gene Name
GO:0003735 IPR000289
GO:0006412 IPR000289
GO:0005622 IPR000289
GO:0005840 IPR000289

4 Ontology Annotations

GO Term Gene Name
GO:0003735 IPR000289
GO:0006412 IPR000289
GO:0005622 IPR000289
GO:0005840 IPR000289

0 Parent Features

956 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
170205 D8RCD2 PAC:15404279 Selaginella moellendorffii 65  
evm.model.supercontig_1.384 PAC:16404326 Carica papaya 65  
evm.model.supercontig_1.386 PAC:16404328 Carica papaya 65  
evm.model.supercontig_77.93 PAC:16426155 Carica papaya 65  
evm.model.supercontig_9.375 PAC:16428285 Carica papaya 65  
29729.m002286 PAC:16806935 Ricinus communis 65  
27553.m000326 PAC:16798675 Ricinus communis 65  
Cucsa.198900.1 PAC:16968654 Cucumis sativus 65  
Cucsa.198910.1 PAC:16968655 Cucumis sativus 65  
Cucsa.198910.2 PAC:16968656 Cucumis sativus 65  
Cucsa.269830.1 PAC:16973462 Cucumis sativus 65  
orange1.1g035463m A0A067FTT2 PAC:18118082 Citrus sinensis 65  
orange1.1g037546m A0A067EIT4 PAC:18115147 Citrus sinensis 66  
AT5G03850.1 Q9SR73 PAC:19669843 Arabidopsis thaliana 64  
AT5G64140.1 P34789 PAC:19665931 Arabidopsis thaliana 64  
AT3G10090.1 Q9SR73 PAC:19661094 Arabidopsis thaliana 64  
Thhalv10015973m PAC:20203796 Eutrema salsugineum 102  
Thhalv10029123m V4L8P5 PAC:20197425 Eutrema salsugineum 64  
Thhalv10002800m PAC:20196907 Eutrema salsugineum 102  
Ciclev10013805m V4ST01 PAC:20798174 Citrus clementina 66  
Ciclev10013157m V4SW27 PAC:20797212 Citrus clementina 114  
Lus10017293 PAC:23165793 Linum usitatissimum 149  
Lus10029320 PAC:23139868 Linum usitatissimum 65  
Lus10013543 PAC:23168744 Linum usitatissimum 212  
Lus10016222 PAC:23142692 Linum usitatissimum 65  
Potri.016G063100.1 A9P8H3 PAC:27011604 Populus trichocarpa 65  
Potri.008G013200.1 PAC:27037939 Populus trichocarpa 65  
Potri.010G245400.1 PAC:26981155 Populus trichocarpa 65  
Gorai.002G154400.1 A0A0D2QDK7 PAC:26795344 Gossypium raimondii 128  
Gorai.005G005700.2 PAC:26801754 Gossypium raimondii 65  

6 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11297922
            11290319
            11114498
            8278557
            1481571
            11875025