Protein Domain : IPR028427

Type:  Family Name:  Peptide methionine sulfoxide reductase
Description:  The oxidation of methionine residues in proteins is considered to be one of the consequences of oxidative damage to cells, which in many cases leads to the loss of biological activity. Peptide methionine sulphoxide reductase (Msr) reverses the inactivation of many proteins due to the oxidation of critical methionine residues by reducing methionine sulphoxide, (MetO), to methionine []. Methionine (Met) can be oxidised to the R and S diastereomers of methionine sulfoxide (MetO). Methionine sulfoxide reductases A (MsrA) and B (MsrB) reduce MetO back to Met in a stereospecific manner, acting on the S and R forms, respectively. Msr is present in most living organisms [, ]. Short Name:  Met_Sox_Rdtase
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0 Child Features

0 Contains

1 Cross References

Identifier
PTHR10173

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0016671 IPR028427
GO:0006979 IPR028427
GO:0030091 IPR028427

3 Ontology Annotations

GO Term Gene Name
GO:0016671 IPR028427
GO:0006979 IPR028427
GO:0030091 IPR028427

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
227932 D8RFU8 PAC:15408525 Selaginella moellendorffii 166  
92187 D8RFR1 PAC:15416234 Selaginella moellendorffii 121  
187336 D8TCD2 PAC:15410631 Selaginella moellendorffii 208  
98474 D8RPC1 PAC:15413789 Selaginella moellendorffii 136  
178515 D8SC11 PAC:15407672 Selaginella moellendorffii 208  
115600 D8SEU5 PAC:15423435 Selaginella moellendorffii 206  
115477 D8SEU2 PAC:15422041 Selaginella moellendorffii 200  
115339 D8SEU4 PAC:15421222 Selaginella moellendorffii 201  
18637 PAC:15402203 Selaginella moellendorffii 98  
18636 PAC:15402202 Selaginella moellendorffii 98  
89699 D8RBX9 PAC:15411087 Selaginella moellendorffii 209  
170312 D8RCU8 PAC:15405112 Selaginella moellendorffii 136  
evm.model.supercontig_13.238 PAC:16407756 Carica papaya 264  
evm.model.supercontig_170.43 PAC:16410864 Carica papaya 246  
evm.model.supercontig_1965.1 PAC:16412331 Carica papaya 214  
evm.model.supercontig_4.29 PAC:16419322 Carica papaya 183  
evm.model.supercontig_6.232 PAC:16423412 Carica papaya 247  
evm.model.supercontig_77.105 PAC:16426060 Carica papaya 200  
29726.m003941 B9RSV2 PAC:16806654 Ricinus communis 143  
29804.m001509 B9RX37 PAC:16809127 Ricinus communis 212  
30147.m014342 B9R9Z9 PAC:16820353 Ricinus communis 261  
30202.m000248 B9SU46 PAC:16823830 Ricinus communis 111  
27471.m000422 B9SXM9 PAC:16798440 Ricinus communis 253  
Cucsa.043450.1 PAC:16953052 Cucumis sativus 247  
Cucsa.093980.1 PAC:16957684 Cucumis sativus 263  
Cucsa.058050.1 PAC:16954614 Cucumis sativus 201  
Cucsa.196260.1 A0A0A0LRY2 PAC:16968238 Cucumis sativus 194  
Cucsa.218650.1 A0A0A0K2R8 PAC:16969703 Cucumis sativus 206  
Cucsa.253810.1 PAC:16972153 Cucumis sativus 139  
orange1.1g028947m A0A067D491 PAC:18124367 Citrus sinensis 201  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10841552
            8994848
            8816789