Protein Domain : IPR004365

Type:  Domain Name:  OB-fold nucleic acid binding domain, AA-tRNA synthetase-type
Description:  The OB-fold (oligonucleotide/oligosaccharide-binding fold) is found in all three kingdoms and its common architecture presents a binding face that has adapted to bind different ligands. The OB-fold is a five/six-stranded closed beta-barrel formed by 70-80 amino acid residues. The strands are connected by loops of varying length which form the functional appendages of the protein. The majority of OB-fold proteins use the same face for ligand binding or as an active site. Different OB-fold proteins use this 'fold-related binding face' to, variously, bind oligosaccharides, oligonucleotides, proteins, metal ions and catalytic substrates. This entry contains OB-fold domains that bind to nucleic acids []. It includes the anti-codon binding domain of lysyl, aspartyl, and asparaginyl-tRNA synthetases (See ). Aminoacyl-tRNA synthetases catalyse the addition of an amino acid to the appropriate tRNA molecule . This domain is found in RecG helicase involved in DNA repair. Replication factor A is a heterotrimeric complex, that contains a subunit in this family [, ]. This domain is also found at the C terminus of bacterial DNA polymerase III alpha chain. Short Name:  NA-bd_OB_tRNA
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0 Child Features

0 Contains

1 Cross References

Identifier
PF01336

12 Found Ins

DB identifier Type Name
IPR004523 Family Aspartyl-tRNA synthetase, archaeal-type
IPR014646 Family Replication factor A protein 2
IPR002312 Family Aspartyl/Asparaginyl-tRNA synthetase, class IIb
IPR004524 Family Aspartate-tRNA ligase, bacterial/mitochondrial-type
IPR004591 Family Replication factor A protein 1
IPR002313 Family Lysine-tRNA ligase, class II
IPR020873 Family 3'-5' exoribonuclease YhaM
IPR006308 Family DNA polymerase III, alpha subunit, Gram-positive type
IPR011149 Family DNA polymerase II small subunit, archaeal
IPR014647 Family CST complex subunit Stn1
IPR016499 Family Nucleic acid binding protein, Rv2694c, predicted
IPR016798 Family Uncharacterised conserved protein UCP021980, OB-fold

1 GO Annotation

GO Term Gene Name
GO:0003676 IPR004365

1 Ontology Annotations

GO Term Gene Name
GO:0003676 IPR004365

1 Parent Features

DB identifier Type Name
IPR012340 Domain Nucleic acid-binding, OB-fold

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
92995 D8RG18 PAC:15422242 Selaginella moellendorffii 563  
441216 D8RHE0 PAC:15406242 Selaginella moellendorffii 815  
79851 D8QXQ7 PAC:15405174 Selaginella moellendorffii 485  
418417 D8S5M5 PAC:15406633 Selaginella moellendorffii 531  
84215 D8R3T7 PAC:15415533 Selaginella moellendorffii 521  
269089 D8SRZ7 PAC:15414224 Selaginella moellendorffii 108  
89304 D8RAZ5 PAC:15408428 Selaginella moellendorffii 636  
440021 D8R9G7 PAC:15401840 Selaginella moellendorffii 279  
272117 D8T3M2 PAC:15401427 Selaginella moellendorffii 536  
evm.model.supercontig_1086.1 PAC:16405515 Carica papaya 620  
evm.model.supercontig_119.38 PAC:16406554 Carica papaya 567  
evm.model.supercontig_1312.2 PAC:16408096 Carica papaya 153  
evm.model.supercontig_137.10 PAC:16408398 Carica papaya 543  
evm.model.supercontig_28.78 PAC:16415976 Carica papaya 644  
evm.model.supercontig_37.195 PAC:16418653 Carica papaya 544  
evm.model.supercontig_41.65 PAC:16419597 Carica papaya 154  
evm.model.supercontig_78.58 PAC:16426236 Carica papaya 572  
evm.model.supercontig_95.40 PAC:16428881 Carica papaya 556  
29703.m001484 B9SFH6 PAC:16806180 Ricinus communis 166  
29827.m002600 B9S1L9 PAC:16810032 Ricinus communis 901  
29912.m005276 B9RK18 PAC:16813155 Ricinus communis 670  
29912.m005418 B9RKD2 PAC:16813295 Ricinus communis 155  
30099.m001677 B9S7X4 PAC:16817698 Ricinus communis 668  
30138.m003969 B9RLN2 PAC:16819335 Ricinus communis 622  
29428.m000317 B9SY11 PAC:16802834 Ricinus communis 607  
28842.m000944 B9SBP3 PAC:16801832 Ricinus communis 585  
28226.m000838 B9SPP8 PAC:16800373 Ricinus communis 242  
Cucsa.322340.1 A0A0A0L503 PAC:16977743 Cucumis sativus 861  
Cucsa.089220.1 PAC:16957111 Cucumis sativus 689  
Cucsa.089220.2 PAC:16957112 Cucumis sativus 689  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            10829230
            7760808
            8990123