Protein Domain : IPR008278

Type:  Domain Name:  4'-phosphopantetheinyl transferase superfamily
Description:  The 4'-phosphopantetheinyl transferase superfamily of proteins transfer the 4'-phosphopantetheine (4'-PP) moiety from coenzyme A (CoA) to the invariant serine of pp-binding. This post-translational modification renders holo-ACP capable of acyl group activation via thioesterification of the cysteamine thiol of 4'-PP []. This superfamily consists of two subtypes: The ACPS type such as ACPS_ECOLI and the Sfp type such as SFP_BACSU. The structure of the Sfp type is known [], which shows the active site accommodates a magnesium ion. The most highly conserved regions of the alignment are involved in binding the magnesium ion. Short Name:  4-PPantetheinyl_Trfase_SF
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1 Child Features

DB identifier Type Name
IPR004568 Domain Phosphopantetheine-protein transferase domain

0 Contains

3 Cross Referencess

Identifier
PF01648
G3DSA:3.90.470.20
SSF56214

1 Found In

DB identifier Type Name
IPR003542 Family Enterobactin synthetase-like, component D

2 GO Annotations

GO Term Gene Name
GO:0000287 IPR008278
GO:0008897 IPR008278

2 Ontology Annotations

GO Term Gene Name
GO:0000287 IPR008278
GO:0008897 IPR008278

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
149567 D8RSR4 PAC:15411597 Selaginella moellendorffii 291  
105813 D8S0V8 PAC:15417874 Selaginella moellendorffii 256  
178621 D8SCF5 PAC:15408510 Selaginella moellendorffii 576  
180454 D8SK64 PAC:15413303 Selaginella moellendorffii 583  
440300 D8RAU7 PAC:15403976 Selaginella moellendorffii 444  
90598 D8RCZ4 PAC:15413500 Selaginella moellendorffii 303  
evm.model.supercontig_5.264 PAC:16421378 Carica papaya 244  
evm.model.supercontig_5.3 PAC:16421417 Carica papaya 178  
29930.m000629 B9SG80 PAC:16814064 Ricinus communis 405  
58361.m000013 B9TBM5 PAC:16829140 Ricinus communis 203  
28629.m000557 B9SWG1 PAC:16801312 Ricinus communis 315  
Cucsa.365030.1 PAC:16981351 Cucumis sativus 330  
Cucsa.253860.1 A0A0A0L5P5 PAC:16972158 Cucumis sativus 788  
Cucsa.282580.1 A0A0A0KRD2 PAC:16974409 Cucumis sativus 276  
orange1.1g020190m A0A067G427 PAC:18117905 Citrus sinensis 329  
orange1.1g025417m A0A067FSY7 PAC:18117907 Citrus sinensis 253  
orange1.1g025416m A0A067FSU3 PAC:18117906 Citrus sinensis 253  
orange1.1g011839m PAC:18106954 Citrus sinensis 476  
orange1.1g011828m PAC:18106953 Citrus sinensis 476  
orange1.1g011865m PAC:18106955 Citrus sinensis 476  
orange1.1g046430m A0A067DXI0 PAC:18113762 Citrus sinensis 260  
orange1.1g023684m A0A067DN32 PAC:18110755 Citrus sinensis 279  
orange1.1g024179m A0A067DS59 PAC:18110756 Citrus sinensis 271  
orange1.1g022776m A0A067GYS0 PAC:18092096 Citrus sinensis 292  
AT3G11470.3 F4J6B2 PAC:19659738 Arabidopsis thaliana 231  
AT3G11470.2 PAC:19659737 Arabidopsis thaliana 300  
AT3G11470.1 Q8VYK1 PAC:19659736 Arabidopsis thaliana 300  
Thhalv10021266m V4LDA4 PAC:20181609 Eutrema salsugineum 286  
Thhalv10005446m V4KXW0 PAC:20199836 Eutrema salsugineum 706  
Thhalv10018351m V4JU15 PAC:20191335 Eutrema salsugineum 562  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            7559576
            10581256