Type: | Family | Name: | ODA1/DCC2 family |
Description: | This entry represents the outer dynein arm (ODA)1/DCC2 family of proteins. Members include ODA1 from lower plants and coiled-coil domain-containing protein 114 (CCDC114) from animals. ODA1 is essential for assembly of the outer dynein arm-docking complex and assembly of the outer dynein arm onto the doublet microtubule []. Similarly, CCDC114 is an essential ciliary protein required for microtubular attachment of the outer dynein arms in the axoneme []. Mutations in the CCDC114 gene are a cause of ciliary dysmotility []. | Short Name: | ODA1/DCC2_fam |