| Type: | Domain | Name: | Thiamin diphosphate-binding fold |
| Description: | This entry represents the thiamin diphosphate-binding fold found in pyruvate dehydrogenases, branched chain alpha-keto acid decarboxylases, phosphoketolases and the pyrimidine binding region of transketolases []. There are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules. Two Pyr and two PP modules can assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules. | Short Name: | THDP-binding |
