Protein Domain : IPR002075

Type:  Domain Name:  Nuclear transport factor 2
Description:  Nuclear transport factor 2 (NTF2) is a homodimer which stimulates efficient nuclear import of a cargo protein. NTF2 binds to both RanGDP and FxFG repeat-containing nucleoporins. NTF2 folds into a cone with a deep hydrophobic cavity, the opening of which is surrounded by several negatively charged residues. RanGDP binds to NTF2 by inserting a conserved phenylalanine residue into the hydrophobic pocket of NTF2 and making electrostatic interactions with the conserved negatively charged residues that surround the cavity [].This entry represent the main structural domain of NTF2 and related domains which are found in other nuclear import proteins. Short Name:  NTF2
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1 Child Features

DB identifier Type Name
IPR018222 Domain Nuclear transport factor 2, eukaryote

0 Contains

1 Cross References

Identifier
PF02136

1 Found In

DB identifier Type Name
IPR014305 Family RNA polymerase sigma-G type, actinobacteria

2 GO Annotations

GO Term Gene Name
GO:0006810 IPR002075
GO:0005622 IPR002075

2 Ontology Annotations

GO Term Gene Name
GO:0006810 IPR002075
GO:0005622 IPR002075

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
7957 D8QZ58 PAC:15406065 Selaginella moellendorffii 106  
230884 D8R4W2 PAC:15417005 Selaginella moellendorffii 126  
7969 D8QRC6 PAC:15406097 Selaginella moellendorffii 106  
169222 D8R9N0 PAC:15423463 Selaginella moellendorffii 123  
evm.model.supercontig_14.183 PAC:16408684 Carica papaya 456  
evm.model.supercontig_198.14 PAC:16412376 Carica papaya 126  
evm.model.supercontig_34.104 PAC:16417832 Carica papaya 469  
evm.model.supercontig_43.74 PAC:16420035 Carica papaya 123  
evm.model.supercontig_59.3 PAC:16423166 Carica papaya 458  
evm.model.supercontig_746.3 PAC:16425809 Carica papaya 383  
evm.model.supercontig_87.25 PAC:16427691 Carica papaya 442  
29842.m003637 B9RXQ5 PAC:16810768 Ricinus communis 125  
29905.m000431 B9SNQ0 PAC:16812714 Ricinus communis 462  
29929.m004636 B9RMD1 PAC:16813875 Ricinus communis 123  
30008.m000802 B9SQT0 PAC:16815572 Ricinus communis 472  
30138.m003961 B9RLM4 PAC:16819327 Ricinus communis 464  
30174.m009097 B9RED0 PAC:16822738 Ricinus communis 493  
30217.m000250 B9T3B3 PAC:16824101 Ricinus communis 478  
29637.m000739 B9SKM6 PAC:16804390 Ricinus communis 465  
Cucsa.086050.1 A0A0A0LUU9 PAC:16956733 Cucumis sativus 125  
Cucsa.095080.1 A0A0A0KW20 PAC:16957823 Cucumis sativus 173  
Cucsa.198290.1 PAC:16968571 Cucumis sativus 472  
Cucsa.255830.2 PAC:16972455 Cucumis sativus 461  
Cucsa.255830.1 A0A0A0L6Y9 PAC:16972454 Cucumis sativus 473  
Cucsa.348880.4 A0A0A0KBZ9 PAC:16979676 Cucumis sativus 449  
Cucsa.348880.1 A0A0A0KBZ9 PAC:16979673 Cucumis sativus 449  
orange1.1g021044m A0A067D1Q6 PAC:18121448 Citrus sinensis 318  
orange1.1g023954m A0A067D164 PAC:18121449 Citrus sinensis 275  
orange1.1g023940m A0A067D5B0 PAC:18121450 Citrus sinensis 275  
orange1.1g033171m A0A067GJC0 PAC:18114704 Citrus sinensis 125  

1 Publications

First Author Title Year Journal Volume Pages PubMed ID
            9533885