Protein Domain : IPR011388

Type:  Family Name:  Sphingolipid delta4-desaturase
Description:  This group represents sphingolipid delta-4 desaturase (DEGS), an integral membrane protein required for sphingosine biosynthesis. It converts D-erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) []. Delta4-desaturated sphingolipids provide an early signal that triggers the entry into both meiotic and spermatid differentiation pathways during Drosophila spermatogenesis []. Dihydroceramide delta(4)-desaturase is a a sphingolipid delta-4 desaturase responsible for the synthesis of sphingosine in Schizosaccharomyces pombe []. Short Name:  DES1/DES2
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2 Child Features

DB identifier Type Name
IPR031195 Family Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2
IPR031196 Family Sphingolipid delta(4)-desaturase DES1

2 Contains

DB identifier Type Name
IPR005804 Domain Fatty acid desaturase domain
IPR013866 Domain Sphingolipid delta4-desaturase, N-terminal

1 Cross References

Identifier
PIRSF017228

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0042284 IPR011388
GO:0030148 IPR011388
GO:0016021 IPR011388

3 Ontology Annotations

GO Term Gene Name
GO:0042284 IPR011388
GO:0030148 IPR011388
GO:0016021 IPR011388

0 Parent Features

300 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
77748 D8QRG3 PAC:15420914 Selaginella moellendorffii 327  
evm.model.supercontig_27.60 PAC:16415682 Carica papaya 326  
29851.m002395 B9RZ74 PAC:16811422 Ricinus communis 334  
Cucsa.126580.1 A0A0A0LSB9 PAC:16961946 Cucumis sativus 324  
orange1.1g020224m A0A067G8D5 PAC:18114885 Citrus sinensis 329  
orange1.1g021532m A0A067G8K0 PAC:18114886 Citrus sinensis 311  
AT4G04930.1 Q9ZPH4 PAC:19648860 Arabidopsis thaliana 332  
Thhalv10028789m V4KJS7 PAC:20197021 Eutrema salsugineum 335  
Ciclev10015896m V4W8L0 PAC:20815935 Citrus clementina 329  
Lus10011189 PAC:23147148 Linum usitatissimum 338  
Lus10018485 PAC:23162089 Linum usitatissimum 338  
Potri.011G050800.1 A0A2K1YFS0 PAC:27002457 Populus trichocarpa 373  
Gorai.010G153100.1 A0A0D2STG1 PAC:26760955 Gossypium raimondii 324  
Gorai.011G026500.1 A0A0D2RFP7 PAC:26809473 Gossypium raimondii 331  
124294 C1N7W7 PAC:27343462 Micromonas pusilla CCMP1545 327  
95334 C1FHJ8 PAC:27397656 Micromonas sp RCC299 326  
Thecc1EG029899t2 A0A061GFF0 PAC:27438037 Theobroma cacao 333  
Thecc1EG029899t1 A0A061GEJ7 PAC:27438036 Theobroma cacao 376  
Migut.M01155.1.p A0A022QND1 PAC:28949063 Mimulus guttatus 334  
Cagra.5070s0009.1.p PAC:28901588 Capsella grandiflora 335  
Glyma.13G240700.1.p I1M269 PAC:30501817 Glycine max 324  
Glyma.15G072800.1.p C6TIK0 PAC:30497688 Glycine max 324  
Brara.I02191.1.p A0A397XVQ8 PAC:30646190 Brassica rapa FPsc 335  
Bostr.2983s0033.1.p PAC:30662751 Boechera stricta 334  
Medtr2g013070.1 A2Q4Q7 PAC:31064630 Medicago truncatula 328  
SapurV1A.0032s0040.1.p PAC:31395411 Salix purpurea 331  
Spipo1G0037700 PAC:31521359 Spirodela polyrhiza 334  
evm_27.model.AmTr_v1.0_scaffold00009.392 W1NJ76 PAC:31568658 Amborella trichopoda 323  
Traes_2AL_3B1D8F110.2 PAC:31998337 Triticum aestivum 317  
Traes_2AL_3B1D8F110.1 PAC:31998336 Triticum aestivum 329  

2 Publications

First Author Title Year Journal Volume Pages PubMed ID
            11937514
            12633877