Protein Domain : IPR001816

Type:  Family Name:  Translation elongation factor EFTs/EF1B
Description:  Translation elongation factors are responsible for two main processes during protein synthesis on the ribosome [, , ]. EF1A (or EF-Tu) is responsible for the selection and binding of the cognate aminoacyl-tRNA to the A-site (acceptor site) of the ribosome. EF2 (or EF-G) is responsible for the translocation of the peptidyl-tRNA from the A-site to the P-site (peptidyl-tRNA site) of the ribosome, thereby freeing the A-site for the next aminoacyl-tRNA to bind. Elongation factors are responsible for achieving accuracy of translation and both EF1A and EF2 are remarkably conserved throughout evolution.Elongation factor EF1B (also known as EF-Ts or EF-1beta/gamma/delta) is a nucleotide exchange factor that is required to regenerate EF1A from its inactive form (EF1A-GDP) to its active form (EF1A-GTP). EF1A is then ready to interact with a new aminoacyl-tRNA to begin the cycle again. EF1B is more complex in eukaryotes than in bacteria, and can consist of three subunits: EF1B-alpha (or EF-1beta), EF1B-gamma (or EF-1gamma) and EF1B-beta (or EF-1delta) [].This entry represents EF-Tu (EF1A) proteins found primarily in bacteria, mitochondria and chloroplasts. Short Name:  Transl_elong_EFTs/EF1B
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0 Child Features

3 Contains

DB identifier Type Name
IPR009060 Domain UBA-like
IPR014039 Domain Translation elongation factor EFTs/EF1B, dimerisation
IPR018101 Conserved_site Translation elongation factor Ts, conserved site

3 Cross Referencess

Identifier
PTHR11741
TIGR00116
MF_00050

0 Found In

3 GO Annotations

GO Term Gene Name
GO:0003746 IPR001816
GO:0006414 IPR001816
GO:0005622 IPR001816

3 Ontology Annotations

GO Term Gene Name
GO:0003746 IPR001816
GO:0006414 IPR001816
GO:0005622 IPR001816

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
420490 D8SC57 PAC:15413045 Selaginella moellendorffii 452  
76038 D8QRM1 PAC:15412647 Selaginella moellendorffii 349  
60716 D8QTN3 PAC:15415584 Selaginella moellendorffii 877  
437874 D8QRL9 PAC:15421257 Selaginella moellendorffii 421  
77102 D8QRL8 PAC:15416266 Selaginella moellendorffii 306  
evm.model.supercontig_14.106 PAC:16408599 Carica papaya 556  
evm.model.supercontig_3091.1 PAC:16417133 Carica papaya 172  
evm.model.supercontig_8.4 PAC:16426632 Carica papaya 396  
29912.m005480 B9RKL9 PAC:16813356 Ricinus communis 972  
30005.m001248 B9SEZ6 PAC:16815481 Ricinus communis 379  
Cucsa.108420.1 PAC:16959730 Cucumis sativus 401  
Cucsa.108420.2 PAC:16959731 Cucumis sativus 401  
Cucsa.108420.3 PAC:16959732 Cucumis sativus 323  
Cucsa.263190.1 A0A0A0LTJ3 PAC:16973229 Cucumis sativus 1122  
Cucsa.263190.2 PAC:16973230 Cucumis sativus 879  
orange1.1g015807m A0A067FS60 PAC:18131815 Citrus sinensis 400  
orange1.1g016633m A0A067FF70 PAC:18131816 Citrus sinensis 386  
orange1.1g016595m A0A067FF70 PAC:18131817 Citrus sinensis 386  
orange1.1g020628m A0A067FIS4 PAC:18131819 Citrus sinensis 323  
orange1.1g016590m A0A067FF70 PAC:18131818 Citrus sinensis 386  
orange1.1g005707m A0A067FGH8 PAC:18116636 Citrus sinensis 681  
AT4G11120.1 Q5XF75 PAC:19648270 Arabidopsis thaliana 395  
AT4G29060.2 F4JMU5 PAC:19648176 Arabidopsis thaliana 709  
AT4G29060.1 Q9SZD6 PAC:19648175 Arabidopsis thaliana 953  
Thhalv10024317m V4MGB9 PAC:20193504 Eutrema salsugineum 979  
Thhalv10024318m V4MGB9 PAC:20193505 Eutrema salsugineum 979  
Thhalv10024316m V4MGB9 PAC:20193503 Eutrema salsugineum 979  
Thhalv10028718m V4L7T9 PAC:20198076 Eutrema salsugineum 392  
Ciclev10020467m V4VU69 PAC:20810816 Citrus clementina 400  
Ciclev10007553m V4UJP0 PAC:20795863 Citrus clementina 754  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            12932732
            15922593
            12762045