Protein Domain : IPR000873

Type:  Domain Name:  AMP-dependent synthetase/ligase
Description:  A number of prokaryotic and eukaryotic enzymes, which appear to act via an ATP-dependent covalent binding of AMP to their substrate, share a region of sequence similarity [, , ]. This region is a Ser/Thr/Gly-rich domain that is further characterised by a conserved Pro-Lys-Gly triplet. The family of enzymes includes luciferase, long chain fatty acid Co-A ligase, acetyl-CoA synthetase and various other closely-related synthetases. Short Name:  AMP-dep_Synth/Lig
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1 Child Features

DB identifier Type Name
IPR010071 Domain Amino acid adenylation domain

2 Contains

DB identifier Type Name
IPR020459 Domain AMP-binding
IPR020845 Conserved_site AMP-binding, conserved site

1 Cross References

Identifier
PF00501

12 Found Ins

DB identifier Type Name
IPR011904 Family Acetate-CoA ligase
IPR005914 Family Acetoacetyl-CoA synthase
IPR012743 Family 4-coumarate--CoA ligase
IPR012694 Family Propionate--CoA ligase
IPR011880 Family Phenylacetate-CoA ligase
IPR011957 Family Benzoate-CoA ligase family
IPR011963 Family 2,3-dihydroxybenzoate-AMP ligase
IPR017523 Family Conserved hypothetical protein CHP03089
IPR017529 Family Acyl-CoA ligase (AMP-forming), exosortase system type 1 associated
IPR017618 Family Dicarboxylate-CoA ligase PimA
IPR017621 Family Cyclohexanecarboxylate-CoA ligase
IPR017720 Family Coenzyme F390 synthetase

2 GO Annotations

GO Term Gene Name
GO:0003824 IPR000873
GO:0008152 IPR000873

2 Ontology Annotations

GO Term Gene Name
GO:0003824 IPR000873
GO:0008152 IPR000873

0 Parent Features

3256 Proteins

DB identifier UniProt Accession Secondary Identifier Organism Name Length
171251 D8RGA2 PAC:15407310 Selaginella moellendorffii 537  
27355 D8RGD5 PAC:15404118 Selaginella moellendorffii 125  
236556 D8TAH6 PAC:15409855 Selaginella moellendorffii 552  
410953 D8RHJ0 PAC:15409527 Selaginella moellendorffii 2385  
231716 D8RIL8 PAC:15419036 Selaginella moellendorffii 502  
94079 D8RHV1 PAC:15421179 Selaginella moellendorffii 184  
8368 D8TD05 PAC:15404372 Selaginella moellendorffii 67  
8362 D8TEE9 PAC:15404368 Selaginella moellendorffii 75  
441669 D8RLV0 PAC:15409452 Selaginella moellendorffii 700  
431974 D8TEJ6 PAC:15404461 Selaginella moellendorffii 243  
96881 D8RLZ2 PAC:15410996 Selaginella moellendorffii 705  
141243 D8QV47 PAC:15408026 Selaginella moellendorffii 693  
165668 D8QVV8 PAC:15415073 Selaginella moellendorffii 668  
266643 D8QU38 PAC:15409861 Selaginella moellendorffii 678  
29158 PAC:15408489 Selaginella moellendorffii 79  
173133 D8RPI4 PAC:15412515 Selaginella moellendorffii 557  
232017 D8RPI3 PAC:15416506 Selaginella moellendorffii 528  
26441 D8RQH3 PAC:15402028 Selaginella moellendorffii 155  
149203 D8RRG7 PAC:15409105 Selaginella moellendorffii 976  
8355 D8TFD0 PAC:15404340 Selaginella moellendorffii 74  
7560 D8TFE0 PAC:15402993 Selaginella moellendorffii 116  
99821 D8RRN3 PAC:15419566 Selaginella moellendorffii 714  
8713 D8TFI5 PAC:15407298 Selaginella moellendorffii 79  
8564 PAC:15405951 Selaginella moellendorffii 79  
415091 D8RUZ8 PAC:15417365 Selaginella moellendorffii 212  
108866 D8S4R0 PAC:15404354 Selaginella moellendorffii 2439  
109501 D8S5Q6 PAC:15404844 Selaginella moellendorffii 727  
268211 D8S6U1 PAC:15412609 Selaginella moellendorffii 532  
177466 D8S6I0 PAC:15404106 Selaginella moellendorffii 542  
177393 D8S6A2 PAC:15403419 Selaginella moellendorffii 544  

3 Publications

First Author Title Year Journal Volume Pages PubMed ID
            2118102
            2254270
            2911486